Biomedical subjects

Runi A Foster

Publications and source records attributed to Runi A Foster.

3 recordsLinked to original sources

PubMed2003

Efficacy trial of live, cold-adapted and inactivated influenza virus vaccines in older adults with chronic obstructive pulmonary disease: a VA cooperative study.

We assessed whether trivalent live, cold-adapted influenza virus (CAIV-T) vaccine provides added protection when co-administered with trivalent inactivated influenza virus vaccine (TVV) in patients with chronic obstructive pulmonary disease (COPD). Subjects (N=2215) were randomly assigned to receive either TVV intramuscularly (IM) and CAIV-T intranasally (TC), or TVV and placebo (TP). The vaccines were well-tolerated. Efficacy of TC compared to TP was not statistically significant and was 0.16 for any influenza virus strain (95% confidence limit (CL): -0.22, 0.43), 0.26 for A (H3N2) virus (95% CL: -0.17, 0.53), and -0.05 for type B virus (95% CL: -1.13, 0.48). However, there was a possible advantage for TC over TP in reducing respiratory consequences of an influenza season measured by pulmonary function and symptoms at end of study.

Administration, Intranasal↗

PubMed2003

Mesalamine-related lung disease: clinical, radiographic, and pathologic manifestations.

Lung injury related to mesalamine (5-aminosalicylic acid) has rarely been reported in patients with inflammatory bowel diseases. Patients present with progressive respiratory symptoms and radiographic abnormalities whose genesis may occur from days to years after initiation of therapy. Although pathologic features overlap with other pulmonary disorders, findings of chronic interstitial pneumonia and poorly formed nonnecrotizing granulomas should prompt consideration of mesalamine-related lung disease in a patient receiving this medication. The authors describe the clinical, radiographic, and pathologic manifestations of mesalamine-related lung disease in three patients and review the literature related to this topic.

Adult↗

PubMed2002

Computerized physician-order entry: are we there yet?

Computerized physician-order entry (CPOE) is a system of hardware and software through which a physician enters orders directly into a computer rather than writing them on paper. The advantages of CPOE include order legibility, improved response time, reduction in adverse drug reactions, reduced cost of care, and improved patient outcomes. The maturation of mobile computing platforms, graphical user interfaces, and wireless technologies are making CPOE more practical for both outpatient and inpatient care. Significant barriers to the implementation of CPOE include the reluctance of physicians to change existing practices, doubt about the possible benefits, increased front-end time to enter orders, and system cost.

Computer Systems↗