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Biomedical subjects

Ruxandra Râjnoveanu

Publications and source records attributed to Ruxandra Râjnoveanu.

3 recordsLinked to original sources

[Imaging in screening and diagnosis of lung cancer].

While the lung cancer is detected, the majority of the patients could not be surgical cured. Thus appears the great necessity of prevention, of a more efficient treatment and the developing of new methods for early detection. The first screening trials for lung cancer had negative results. None of the studies had no prove in decreasing of mortality by screening for lung cancer. The lack of sensitivity of thoracic radiographs and sputum cytology was leading the investigators to use the monoclonal antibodies in detecting the neoplastic changes in sputum, the spiral computerized tomography with low dose of radiations, the autofluorescence bronchoscopy and more recent the positron emission tomography, offering the possibility of reducing mortality by early detection in lung cancer.

Antibodies, Monoclonal↗

[Rare histological type of pulmonary adenocarcinoma--two clinical cases].

Two cases of primary signet-ring cell adenocarcinoma of the lung are presented. The patients were: a 53-year-old man with a left lung mass and a 40-year-old woman with a right lung mass. Endobronchial biopsy performed after fiber-bronchoscopy reveal this rare histological type for pulmonary localizations of neoplasms. It is well known that this histological type is found in digestive localizations of neoplasms, especially gastric, but in these two cases we excluded such a neoplasm. The tumor we found in these two cases is a very rare intrapulmonary neoplasm with a poor clinical course and prognosis. Signet-ring cell adenocarcinoma is a recently described neoplasm whose histology is different from most lung adenocarcinomas and represented a spectrum of malignant potential. Little is known of the behaviour of more malignant subtype.

Adult↗

[Diagnostic difficulties in generalized tuberculosis--a case report].

Generalized tuberculosis (characterized by the presence in several organs of small tuberculous granulations surrounded by normal tissue) is becoming a more and more seldom disease, having an unpredictable evolution and prognosis. The diagnosis is often difficult. We present the case of a young woman, 29 years old, in which the diagnosis established in a late stage could have been fatal.

Adult↗