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Biomedical subjects

Ruxandra Ulmeanu

Publications and source records attributed to Ruxandra Ulmeanu.

10 recordsLinked to original sources

[Epidemiology of lung cancer].

This articles aims to review epidemiological aspects related to lung cancer (LC). The risk factors for LC are external factors and host factors. One can note an increasing incidence of LC in women, related to considerable increase of smoking habits in this group. Mortality by LC is related to number of cigarettes smoked daily and how deep the smoke is inhaled. Air pollution and occupational factors increase the LC risk among industrial workers. Pre-existing lung diseases (pulmonary fibrosis, COPD or bronchial asthma) can increase the risk for LC. There are also genetic factors involved in LC. Carcinogenesis is a multi-stage process. In each stage exogenous and endogenous factors are involved, determining mutations on the dominant oncogenes and on genes suppressing tumor appearance.

Age Distribution↗

[A new therapeutic option for diabetes patients].

Type I diabetes often raises therapy problems because the patients compliance is related to the insulin injections needed all life long. In these circumstances, the authors review a new therapeutic option--inhaled insulin. In order to be convincing about this future treatment, the article reviews: the history of the discovery, pharmacokinetic aspects, results of clinical studies and patients adherence to this new kind of substitution treatment of human insulin deficiency.

Administration, Inhalation↗

[Sequential approach in a case of tracheal hemangioma: segmental tracheal resection after Nd-YAG laser application].

Tracheal tumors of malignant or benign origin are very rare. The symptoms may mimic asthmatic crisis, dyspnea at rest or light efforts appear only when the tumor obstructs 60% of the tracheal diameter. We present the case of a 50 year old patient, ex-smoker with symptoms present 5 years before admittance with dyspnea and small hemoptysis. Diagnosis was based on bronchoscopic examination, CT scan and histological examination of the resection sample revealing a rare benign tracheal tumor: a hemangioma. The sequential treatment of the disease is presented: interventional endoscopy and surgical resection. The excellent postoperative evolution emphasized the diagnostic and therapeutic value of bronchoscopy as well as surgery in benign tracheal tumors.

Anastomosis, Surgical↗