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Biomedical subjects

S A Adebonojo

Publications and source records attributed to S A Adebonojo.

47 records · Page 3Linked to original sources

Teratoid tumors of the mediastinum.

Anterior mediastinum is the third commonest location for teratoid tumors besides the ovaries and the testes. Although there is still some confusion about the classification of these tumors, most authors now agree that the term dermoid cyst should be used for cystic lesions containing ectodermal and mesodermal elements. Teratoma should be reserved for solid or cystic lesions containing derivatives of all the three germ layers. The clinical manifestations offer no clue to their malignant potentiality. Chest roentgenogram, tomogram and esophagogram are useful, and aortic arch studies may be indicated in some cases to exclude aortic aneurysms. Surgical excision offers the best method of diagnosis and treatment. The prognosis is excellent for benign teratoids but poor for malignant teratoids, especially in children and young adults.

Adult↗

Evaluation and management of solitary pulmonary nodules.

The incidence of malignancy in solitary pulmonary nodules found on routine chest roentgenographic survey is unknown but may be as high as 20 per cent. The greatest dilemma confronting most physicians involved in the primary care of patients with solitary pulmonary nodules is sorting out those nodules that can be safely watched from those that should be surgically removed. Certain roentgenographic features of these nodules have been found to be helpful in diagnosis. The only two features that can indicate benign lesions are the presence of dense or concentric calcifications and the stability of the lesion over a period of more than two years. The final decision to operate or not may depend on comparison with old films. Pulmonary nodules present for more than two years without any change in size can be safely followed without operation. Operation is indicated in most newly discovered noncalcified nodules larger than 4 cm and for lesions causing obstructive symptoms.

Calcinosis↗

Congenital aneurysm of the pulmonary artery: a case report.

A case of congenital aneurysm of the left pulmonary artery in a 52-year-old Nigerian woman is presented. She presented with a transient history of cough and epigastric pains. A chest radiograph revealed a rounded left hilar mass just superior to the left main bronchus, and pulmonary angiography confirmed the presence of fusiform aneurysm of the left pulmonary artery. At cardiac catheterization, there was pulmonary hypertension (80 mmHg). There was no associated congenital cardiac malformation. The electrocardiograph showed right ventricular hypertrophy. The patient remains asymptomatic to date. This is the fourth known report of pulmonary aneurysm in an African. The rarity of pulmonary artery aneurysms is stressed.

Aneurysm↗

Management of chest trauma: a review.

The incidence of chest trauma has increased significantly since the turn of the century especially in developed countries where rapid means of transportation has become part of daily life. Although gunshot wounds (GSWs) were the commonest causes of chest trauma in wartime, road traffic accidents (RTAs) have become the scourge of peacetime and modern civilization. Chest trauma is more common in males during the 2nd to the 5th decades of life with an average age of 40 years reducing their life expectancy by another 40 years at the most productive and active period of their lives. Despite improvement in ambulance service and rapid mobilization of victims from the scene of accident, about 10% of chest injured patients will die on the spot and another 5% die within an hour of reaching the hospital. Of the remaining 85%, five percent will require emergency thoracotomy for various reasons while 80% will respond to resuscitative measures and tube thoracostomy drainage alone. The primary aims in the management of chest trauma are prompt restoration of normal cardiorespiratory functions, control of haemorrhage, treatment of associated injuries and prevention of sepsis. Although the overall survival rate of trauma has improved in recent years, deaths are often due to airway obstruction, exsanguinating haemorrhage, flail chest, tension pneumothorax, cardiac tamponade and associated intracranial, intraabdominal and skeletal injuries.

Accidents, Traffic↗

Pericardioperitoneal shunt for massive recurrent pericardial effusion in patients with endomyocardial fibrosis.

Massive recurrent pericardial effusion in patients with endomyocardial fibrosis presents a therapeutic challenge. Repeated pericardiocentesis and creation of a pericardial window is associated with significant morbidity and mortality in these critically ill patients. A new pericardioperitoneal shunt using a Holter valve and Harris catheter has been devised to solve some of these problems.

Adolescent↗