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Biomedical subjects

S A Butrova

Publications and source records attributed to S A Butrova.

At least 19 recordsLinked to original sources
PubMed1984

[Obesity].

Explore the source record for details and available documents.

Adult↗
PubMed1980

[Effect of teralen on brain bioelectrical activity in Itsenko-Cushing disease and hypothalamic syndrome patients].

Theralen effect on the brain electric activity was studied in 12 patients with Icenko-Cushing's disease and 8 persons with the hypothalamic syndrome. Theralen was shown to potentiate theta-activity in patients suffering from the diseases of short duration in contrast to healthy subjects. Patients with Icenko-Cushing's disease showed a delayed reaction to theralen as compared to subjects with the hypothalamic syndrome. Theralen was ineffective in both groups of patients suffering from above diseases for over 3 years.

Adolescent↗
PubMedDate not supplied

[Induced and spontaneous prolactin secretion in young, obese women].

Prolactin reactions in response to insulin hypoglycemia and prolactin levels were examined in 20 obese women of reproductive age at various time of the day. In one group prolactin response to stimulation with insulin hypoglycemia was normal, in another group an increase in the level of prolactin was unnoticed. Both groups were compared with healthy controls. Two types of obesity (upper and lower) were investigated. A conclusion has been made that the absence of prolactin reaction in response to insulin hypoglycemia and an insufficient rise of prolactin at night are noted more frequently in women with upper type of obesity suggesting more profound endocrine derangements in them as compared to women with lower type obesity.

Adult↗
PubMedDate not supplied

[Effect of large doses of reserpine on the hypothalamo-hypophyseal-adrenal system in Itsenko-Cushing's disease].

The results of study of the hypothalamo-hypophysio-adrenal system in patients with Itsenko-Cushing's disease under the influence of high reserpine doses are presented. An increase of plasma ACTH and cortizol level and disturbance of the 24-hour rhythm of their secretion was noted in the patients. High reserpine doses led to the fall of ACTH and cortizol secretion, without any normalization of their secretion rhythm in the course of 24 hours. A test with metopyron carried out before and after the reserpine prescription pointed to the increase of the ACTH reserve under the influence of high reserpine doses.

17-Hydroxycorticosteroids↗
PubMedDate not supplied

[The effect of luliberin and sulpiride on the secretion of gonadotropic hormones and prolactin in patients with obesity].

The role of dopamine (DA) in the secretion of gonadotropic hormones was studied in women with obesity and normal body mass. Tests with sulpiride (peripheral antagonist of DA-receptors), sulpiride LH-RH and thyroliberin were made. Basal and LH-RH-stimulated secretion of gonadotropins and prolactin (PRL) was studied to reveal the relationship of their secretion with the status of the hypothalamohypophyseal system. It was shown that the blockade of peripheral DA receptors did not result in an increase in the basal and LH-RH-stimulated secretion of LH either in healthy women or in women with obesity at the normal basal level of gonadotropic hormones. Hyperprolactinemia caused by sulpiride or LH-RH, did not lower LH secretion during the entire period of investigation. There were no differences either in the basal level of gonadotropic hormones or in their ejection in response to LH-RH administration in women with normal and excess body mass. Stimulation of PRL secretion in response to LH-RH was found in patients with exogenous-constitutional obesity and minimum signs of diencephalic pathology. Slight inhibition of PRL secretion after LH-RH administration was noted in women with obesity of hypothalamic type and unstable type of disorder of EEG. The absence of changes in PRL secretion was noted in women with strongly marked hypothalamic signs of the disease.

Adolescent↗
PubMedDate not supplied

[Sensitivity of the hypothalamo-hypophyseal system to dexamethasone administered at different times of the day in obesity].

The paper is concerned with the results of a study of the circadian rhythm of cortisol secretion and sensitivity of the hypothalamohypophyseal system to small doses of dexamethasone administered in different time of a day to patients with obesity. Disturbance of the circadian rhythm of cortisol secretion resulting in change of the nature of cortisol discharge in the second half of a day, was revealed. Three groups of patients were defined with relation to the type of response of the hypothalamohypophyseal system to dexamethasone administration: with normal, paradoxical and hypersensitive reactions. The results of the study of the circadian rhythm and response of the hypothalamohypophyseal system to dexamethasone were indicative of hypothalamic disturbances in obesity. The authors emphasized the relationship between the nature of sensitivity of the hypothalamohypophyseal system to dexamethasone and age at which the disease developed.

Adult↗