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Biomedical subjects

S A Cherniakevich

Publications and source records attributed to S A Cherniakevich.

At least 19 recordsLinked to original sources

[Surgical treatment of ulcerous pyloroduodenal stenosis].

From 1990 to 2001 531 patients underwent surgery for ulcerous pyloroduodenal stenosis, from 1990 to 1995 312 operations were performed with lethality 0.9%, from 1996 to 2001--312 surgeries with one lethal outcome (0.4%). Surgical policy is based on a differential approach to choice of surgical method with consideration of stage of stenosis and level of gastric secretion, and also surgical risk. Organ-saving operations including laparoscopic vagotomy were performed in forming and compensated stenosis. At late stages (sub- and decompensated stenosis) resections (chiefly with vagotomy) were performed. In long-term period excellent and good results were achieved in 91.4% patients.

Digestive System Surgical Procedures↗

[Results of pre- and postoperative treatment of complicated duodenal ulcers with proton pump inhibitors ].

Benefit of monotherapy of duodenal ulcers by lanzap in 36 patients was compared to that of combined therapy including panitidin in 26 patients. Lanzap brought about ulcer healing within 7-10 days in 55.6%, within 14-16 days ulcer scarring was observed in 35 patients (97.2%). Ulcer healing progressed depending on ulcer size. Combined treatment with ranitidine promoted ulcer scarring in 14-16 days in 73% patients. Lanzap monotherapy in preoperative period promoted fast healing of ulcer defect anf provided optimal conditions for surgery.

2-Pyridinylmethylsulfinylbenzimidazoles↗

[Comparative experimental enzymatic activity and clinical efficacy of pepsin K and abomin].

Hen pepsin (pepsin K) in the experiment on proteolytic activity of hemoglobin surpasses porcine pepsin (abomin) with pH of medium 2 in 1.7 times, with pH of medium 3 in 44 times, that makes it more acceptable for treatment of enzymatic insufficiency of stomach. In the clinic reception of pepsin K in tablets for 4 weeks had a positive effect for all 10 patients after the surgical intervention on the stomach. The results were good for seven of them, and satisfactory for three patients.

Animals↗

[Etiology of recurrent ulcers after selective proximal vagotomy].

The work analyses the results of late-term follow-up of 525 patients who underwent selective proximal vagotomy (SPV) in different variants. The results were gained on the basis of long-standing follow-up with the use of the complex dispensary method. The frequency of peptic ulcer recurrences after SPV was 10%. The main causes of the recurrences were: incomplete vagotomy of the parietal cell zone and inadequate selection of patients for this intervention. Finally, the authors demonstrate the clinico-pathogenetical variants of the course of peptic ulcer when SPV cannot correct the existing disorders and the therapeutic effect of the operation is doubtful. All the aforesaid dictates the need for specialization of surgeons-gastroenterologist who are engaged in this problem and for strict determination of the indications for SPV.

Duodenal Ulcer↗

[Results of truncal and selective proximal vagotomies combined with stomach-draining surgery in ulcer-related pyloro-duodenal stenosis].

The authors have shown that remote results of draining operations in combination with truncal vagotomy in ulcerous pyloroduodenal stenosis proved to be similar to results of their combination with selective proximal vagotomy in practically all the parameters. Advantages of the selective proximal vagotomy due to somewhat less amount and less degree of postoperative functional disorders observed after this intervention become practically levelled down by a considerably greater amount of recurrences of ulcers after it as compared with truncal vagotomy and drainage of the stomach.

Adult↗