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Biomedical subjects

S A DeLuca

Publications and source records attributed to S A DeLuca.

At least 19 recordsLinked to original sources

Growth plate injuries: Salter-Harris classification.

Fracture of the growth plate is an injury unique to childhood. Most such fractures heal without permanent deformity. A small percentage, however, are complicated by growth arrest and subsequent deformity. The Salter-Harris classification of growth plate injuries aids in estimating both the prognosis and the potential for growth disturbance. The Salter-Harris system classifies growth plate fractures into five groups: type I, fracture through the growth plate; type II, fracture through the growth plate and metaphysis; type III, fracture through the growth plate and epiphysis; type IV, fracture through the growth plate, epiphysis and metaphysis, and type V, crush or compression injury of the growth plate.

Biomechanical Phenomena

Imaging of sinonasal tumors.

Imaging of the paranasal sinuses and the nasal cavity provides important anatomic information in the evaluation of suspected neoplasia. The primary modalities employed are conventional films, computed tomography (CT) and magnetic resonance imaging (MRI). Although plain sinus films remain the screening procedure of choice, CT is the preferred modality for more detailed assessment of the paranasal sinuses and the nasal cavity. When soft tissue discrimination is required, MRI is indicated. Imaging studies are used to define the limits of disease, not to diagnose malignancy.

Humans

Primary tracheal neoplasms: recognition, diagnosis and evaluation.

Primary neoplasms of the trachea are much less common than malignancies of the larynx and lungs. Tracheal neoplasms account for less than 0.1 percent of all neoplasms. Their importance lies in the fact that they may initially be misdiagnosed, resulting in a delay in diagnosis ranging from months to years. The most common benign tracheal neoplasms are hemangiomas, squamous papillomas and fibromas. The most common tracheal malignancy is squamous cell carcinoma. Symptoms of these lesions are usually related to airway obstruction and include wheezing, dyspnea and cough.

Adult

Tuberous sclerosis.

Tuberous sclerosis is an inherited disorder characterized by a triad of signs--mental retardation, seizures and adenoma sebaceum. The hamartomas that commonly affect multiple organ systems can be seen on plain film radiography. Computed tomography and ultrasonography are useful for assessing whether lesions are present in the abdomen, kidneys and brain. The hamartomas tend to bleed, causing symptoms and prompting the need for evaluation.

Brain

Mediastinal granuloma secondary to histoplasmosis.

Mediastinal granuloma is one of the many potential clinical manifestations of infection with Histoplasma capsulatum. Plain radiographs, computed tomography and magnetic resonance imaging can help identify intrathoracic adenopathy, calcification, and compression or invasion of vital structures.

Adult

Kartagener's syndrome.

Kartagener's syndrome is characterized by situs inversus, chronic paranasal sinusitis and bronchiectasis. The pathogenesis of this rare condition is an ultrastructural defect that results in immotile cilia. Radiologic features may include findings consistent with bronchiectasis.

Abnormalities, Multiple

Synovial cell sarcoma.

Synovial cell sarcoma frequently presents as a painful periarticular mass in the lower extremity of a young male patient. The mass may appear encapsulated and is calcified in approximately 50 percent of cases. Surgery is the mainstay of therapy, with radical resection often necessary to prevent local recurrence. The maximal five-year survival rate is 40 percent. Survival is associated with small lesions, absence of metastases and histologically low-grade lesions in younger patients.

Adolescent

Ankylosing spondylitis.

Associated with the presence of HLA-B27 antigen, this inflammatory disorder of unknown etiology predominantly affects young adult men. Most patients present with low back pain and stiffness. Radiographs may show erosions, sclerosis and ankylosis in the pelvis and in the discovertebral, apophyseal, costovertebral and atlantoaxial joints. Hips and shoulders are the peripheral joints most commonly affected. Although most of the axial and appendicular skeleton may be involved, bilateral and symmetric sacroiliac involvement is the hallmark of ankylosing spondylitis.

Humans

Lymphoma presenting as a periorbital tumor.

Lymphoma is a common tumor of the periorbital region. Facial radiographs may show a soft tissue mass. Radiologic differential diagnosis of orbital masses is difficult. Computed tomographic scanning with intravenous contrast medium is useful in diagnosing and staging neoplasms in this area.

Diagnosis, Differential

Hazards of magnetic resonance imaging.

Magnetic resonance imaging uses powerful magnetic fields and a radiofrequency pulse to provide a diagnostic image. Physicians must identify patients with metallic internal implants, pacemakers and cochlear implants before MRI scanning to prevent serious injury. Some patients also experience severe anxiety from the confinement and noise during the examination. Careful evaluation of these potential problems should always be undertaken before performing an MRI examination.

Equipment Safety

Radiographic features of gout.

Hyperuricemia is the hallmark of gout. Deposition of monosodium urate crystals in the joints and periarticular soft tissues can lead to arthritic changes. Radiographic features include periarticular soft tissue swelling, "punched-out" bony erosions and joint space narrowing. Although gout has a predilection for the first metatarsophalangeal joint, it may also affect the feet, hands, wrists, elbows and knees.

Finger Joint

Solitary pulmonary metastasis from melanoma.

Malignant melanoma often presents with multiple-organ involvement. Pulmonary metastases are present in more than 50 percent of patients with a diagnosis of melanoma at autopsy. Metastases to the lung may be solitary or multiple. Computed tomographic scanning is the most sensitive radiologic method for detecting these pulmonary lesions.

Aged

Saccular aneurysms of the thoracic aorta.

In the evaluation of thoracic masses adjacent to vascular structures, aneurysms must be considered as a possible etiology. Particular consideration must be given to this possibility before percutaneous biopsy is performed. While contrast-enhanced computed tomography or magnetic resonance imaging is usually sufficient for making the diagnosis, angiography remains the gold standard for characterization and preoperative planning.

Aged

Transient osteoporosis of the hip.

This uncommon entity typically presents in young to middle-aged patients. The clinical features are progressive pain and a limp with no history of trauma. Bone density in the affected femur is progressively affected. The process is self-limited, with gradual improvement of symptoms and bony mineralization within several months.

Adult

Thyroglossal duct cyst.

Thyroglossal duct cyst is a midline congenital nonodontogenic cyst seen predominantly in children. The clinical history and physical examination, along with characteristic radiographic findings, enable the physician to make a preoperative diagnosis with a high degree of certainty. Surgery is the definitive treatment.

Child

Traumatic pancreatic transection.

Pancreatic contusion or transection may result from blunt or penetrating trauma. Considerable morbidity and mortality may occur if the injury is not diagnosed and treated promptly. Clinical diagnosis of pancreatic injury due to blunt trauma is difficult, because the symptoms are often delayed and nonspecific. Computed tomographic scanning is the method of choice for the diagnosis of pancreatic injury, although abdominal ultrasound may be particularly useful in children. Endoscopic retrograde cholangiopancreatography is used to assess ductal integrity.

Abdominal Injuries