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Biomedical subjects

S A Frolov

Publications and source records attributed to S A Frolov.

7 recordsLinked to original sources

[Laparoscopic surgery of rectal cancer (comparative results of laparoscopic and open abdominal resection)].

Attempt to perform surgery with laparoscopic technologies was taken in 80 (50.6%) from 158 patients with cancer of the rectum. Surgery was finished only with laparoscopy in 64 (80.0%) cases, conversion to open operation was necessary in 16 (20.0%). Open anterior surgery was performed in 78 patients. Patients after laparoscopic operations required less narcotic analgesics (63.3 +/- 1.5 and 105.0 +/- 2.2 mg, respectively) and demonstrated earlier restoration of peristalsis (31.7 +/- 1.2 hours and 59.4 +/- 1.7 hours, respectively). Rate of complications after laparoscopic surgeries was 9.4%, after open--25.6%. Three-year survival after laparoscopic anterior resection was 91.7%, after open--84.6%. Survival of patients depends of depth of invasion into intestinal loop and lesion of lymphatic nodes, irrespective of surgical method.

Adult↗

[Laparoscopic rectum repair].

A reliable and simple method of allograft fixation in laparoscopic posterior-loop rectopexy (LPR) was developed. The study was carried out on 40 cadavers, peak effort of separation of the net fixed to the sacrum by various methods was evaluated. Effort of separation in fixation of the net by sutures was 10.1 +/- 2.12 kg, in fixation by hernial stapler--1.13 +/- 0.36 kg, stapler "Pro-Tack"--6.38 +/- 1.85 kg, in fixation of the net by the new device--8.9 +/- 0.75 kg. From 1995 till 1999 LPR was performed with the new device in 15 patients, the open posterior-loop rectopexy (OPR) with fixation of the net by non-absorbable sutures--in 16 patients. In LPR intraoperative blood flow was twice as small (146.0 +/- 79.2 ml) as in OPR (275.6 +/- 76.9 ml). Mean time of LPR was 183.1 +/- 69.8 min, OPR--211.3 +/- 57.9 min. Relief of pain after LPR enabled with reduction of narcotic analgetics requirement (58.3 +/- 1.5 mg). Mean dose of narcotic analgetics after OPR was 93.2 +/- 1.4 mg. The proposed method of allograft fixation and device for it realization are effective and meet all requirements.

Analgesics, Opioid↗

[Long-term results of formation of smooth muscle sphincter in the perineal colostomy area in patients after rectal extirpation].

The authors discuss an original method for formation of a smooth-muscle cuff from the wall of a pulled-through colon in the region of a perineal colostoma. It was applied in 89 patients who had undergone extirpation of the rectum for malignant neoplasms. The smooth-muscle sphincter was formed during removal of the rectum in 72 patients and no earlier than 2 years after the extirpation in 17 patients. Inflammatory complications developed in the region of the perineal colostoa in the early postoperative period in 13.5% of cases. They were due to necrosis of the distal part of the pulled-through intestine in 3.4% of cases. There were no fatal outcomes. The late-term results were studied in follow-up periods of up to 7.5 years. Satisfactory functional results were produced in 83% of the patients. Physiological examination showed the presence of a functioning sphincter in the region of the perineal colostoma.

Adult↗

Method of creation of a smooth-muscle cuff at the site of the perineal colostomy after extirpation of the rectum.

The authors present a method of creation of a smooth-muscle cuff at the site of the perineal colostomy in 36 patients who have undergone extirpation for malignant neoplasms of the low ampulla recti. Creation of the smooth-muscle sphincter mechanism was performed during the process of removal of the rectum in 29 patients, whereas it was done two to eight years after extirpation of the rectum in seven patients. Inflammatory complications were observed in the perineal colostomy area during the early postoperative period in eight patients. These complications were accounted for by necrosis of the distal colon and transplanted muscle in two patients. There were no deaths. Satisfactory functional results were seen in 22 of 26 patients six months after surgery. Physiologic studies show that there is a functioning sphincter at the site of the perineal colostomy.

Adult↗