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Biomedical subjects

S A Galetzki

Publications and source records attributed to S A Galetzki.

3 recordsLinked to original sources
PubMed1985

Oncogene expression in human tumors.

The expression of 9 oncogenes in primary tumors and in human tumors passaged in nude mice was tested: a total of 28 tumor types was analyzed. Oncogenes src, fps, and mos were not expressed in any of the tumors tested but oncogene myc was transcribed in most of the tumors and myc was over-expressed in 3 tumors passaged in nude mice (Ewing sarcoma, large intestine carcinoma and kidney carcinoma) and in primary fibrous histiocytoma. Enhanced transcription of ras and fos genes was observed nonspecifically in different tumors. Oncogene sis was activated specifically in metastases of different tumors in lymph nodes.

Animals↗
PubMed1980

RSV-transformed mammalian cells: an analysis of RNAs specific for exogenous and endogenous viruses.

A marked decrease in expression of RSV-specific sequences was observed in cryptovirogenic RSV-transformed RVP3 murine cells during passaging. Simultaneously an increase in expression of sequences specific for C-type murine viruses was observed both in these cells and other RSV-transformed murine cells. No activation of C-type viral genome was detected in spontaneous murine lung tumors and in methylcholanthrene-induced murine tumors. Four types of virus specific RNAs were found in XC cells: the 30--35 S, the 26--28 S, the 21--23 S and the 15--18 S type. The 9--14 S RNA was the dominant species of RSV-specific RNA in TWERC cells.

Animals↗