Biomedical subjects
Publications and source records attributed to S A Gromova.
Roakkutan was used in the treatment of 49 patients with severe acne vulgaris and 8 patients with rosacea. The treatment was highly effective. The primary and maintenance daily doses of the drug are suggested and the terms of therapy defined.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Direct action of ultraviolet radiation with wavelength of 280, 310 and 365 nm increased the amplitude of neocortex EEG and enhanced the epileptiform activity in the penicillin--induced epileptic focus, whereas action of superthreshold radiation with wavelength of 580 and 630 nm decreased the EEG amplitude and suppressed the epileptiform activity. The mechanism of ultraviolet radiation effect on the neocortical electrical activity seems to be based on changes in permeability of neuronal membranes for Na and K ions and on following depolarization of the membranes, whereas the action of visible radiation leads to the heat injuring of neurons in the irradiated area which evokes irreversible suppression of their activity and reducing of their EEG amplitude.
The action of optical radiation on neocortical bioelectrical activity and on a penicillin-induced epileptic focus was investigated. The direct action of ultraviolet (UV) radiation with wavelengths 280, 310, and 365 nm was shown to increase the amplitude of the spontaneous EEG and to potentiate epileptiform activity, whereas the action of subthreshold radiation with wavelengths of 580 and 630 nm caused a reduction of EEG amplitude and inhibition of epileptiform activity. On the basis of the writers' own results and data in the literature it is postulated that the mechanism of action of UV radiation on neocortical electrical activity is based on changes in permeability of neuronal membranes to Na and K ions and subsequent membrane depolarization, whereas the action of visible radiation leads to thermal injury to the neurons in the irradiated zone, inducing irreversible suppression of their activity and a decrease in amplitude of the EEG.