Biomedical subjects
Publications and source records attributed to S A Klopotskiĭ.
The most frequent clinical manifestation of renal lesion in patients with paraneoplastic syndrome is nephrotic syndrome, which is associated with a special morphological type of renal lesion, membranous nephropathy (MN). The latter accompanies various types of cancer. The article contains case reports of patients with paraneoplastic MN, which was coped with after radical antitumoral treatment.
Two groups of patients with terminal chronic renal failure (TCRF) treated from 1970 to 1979 (group 1) and in 1980-1989 (group 2) have been compared in respect to treatment results. All the patients underwent programmed hemodialysis performed on different equipment and according to different regimens. The results of group 2 appeared better: the lethality decreased by 18%, mean survival from 6 months to 4.5 years, up to half of the patients were able to receive hemodialysis procedures outpatiently, 30% of the patients were prepared to receive a renal transplant. The above positive shifts were achieved due to utilization of updated equipment, improved water purification, 3-stage technique of hemodialysis, antianemic drug eprex and vanalpha against osteodystrophy.
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