Biomedical subjects

S A Korovkin

Publications and source records attributed to S A Korovkin.

5 recordsLinked to original sources

PubMed1989

[Methodology of determining Yersinia pestis antigens using dot-immunologic analysis].

The technique of dot-immunoassay on nitrocellulose filters is described for the detection of the vital infection (VI) agents. The results are read visually (qualitatively) and instrumentally (quantitatively). The method is highly sensitive (3.2 +/- 0.8 ng/ml of fraction I) and specific, cost-effective, simple, and available for laboratories engaged in VI diagnosis.

Antigens, Bacterial↗

PubMed1988

[Quantitative determination of specific plague fluorescent immunoglobulin activity using pulse flow cytofluorometry].

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Antibodies, Bacterial↗

PubMed1983

[Test for differentiating plague and pseudotuberculosis cultures].

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Bacteriological Techniques↗

PubMedDate not supplied

[The biochemical aspects of the pathogenicity of the causative agent of plague].

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Animals↗

PubMedDate not supplied

[A gene expression study and the isolation and immunobiological properties of the iron-regulated membrane proteins of the plague microbe].

The study has examined how the plague bacillus expresses genes of two high-molecular weight (190 and 240 kD) iron-regulated membrane proteins (HMWP). The latter were purified and assayed for their immunobiological properties in vitro and in vivo. DNA-probing (at E.Carniel's Laboratory, Pasteur Institute, Paris) has indicated that Yersinia pestis strains having genes that code for HMWP synthesis circulate in the natural foci of plague which are situated in the former USSR. The use of HMWP in combination with live plague vaccine EV was found to greatly enhance its immunogenicity.

Animals↗