Biomedical subjects
Publications and source records attributed to S A Likhachev.
This paper gives a description of the mechanisms of inhibition of the vestibulo-ocular reflex by the gaze mechanisms in patients with unilateral lesion of peripheral compartments of the vestibular system at the stage of decompensation and subcompensation.
In 40 patients with unilateral injury of the peripheral compartment of the vestibular system in the stage of decompensation (Group 1) and subdecompensation (Group 2), the vestibulo-ocular reflex (VOR) was investigated during sinusoidal rotation with the eyes closed. Group 1 patients showed a significant asymmetry of the VOR coefficient and a distinct shift of the VOR displacement towards injury during sinusoidal stimulation of any intensity. Group 2 patients displayed similar but less significant changes.
The oculovestibular reflex is characterized by the reactivity coefficient and phase shift. The reactivity coefficient is a relative value which makes it possible to evaluate oculovestibular interaction and to describe the normal reactivity of the vestibular system which is far less variable than the vestibular nystagmus norm. Phase shift is defined as a delay or lead of the oculomotor reaction (in degrees) when compared to the stimulus generating it. Methods for measuring the reactivity coefficient and phase shift of the oculovestibular reflex are described.
Vestibulo-ocular interaction was investigated in 25 healthy subjects, aged 16-48 years. They showed a nearly complete inhibition of the vestibulo-ocular reflex (VOR) during rotation and gaze fixation at a target rotating together with the chair; the reactivity coefficient was no more than 0.05. During rotation with the eyes closed a specific type of the VOR phase shift was detected. These observations on normal subjects can be used for reliable interpretation of vestibulo-ocular interaction in patients with vestibular disorders.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
The authors studied the time course of spontaneous nystagmus and parameters of vestibuloocular interaction in patients with reflex syndromes of cervical osteochondrosis accompanied by vestibular dysfunction, under the influence of manual therapy. It has been established that the most informative parameters, capable of reflecting in an objective manner the dynamics of vestibular dysfunction in the course of treatment are intensity of spontaneous nystagmus and reaction of suppression of vestibuloocular reflex by gaze.
Suppression of vestibulo-ocular reflex by deviation of eyes was studied in 30 patients with various vestibular disorders. Method of eyes abduction based on Alexander's law was established to increase markedly diagnostic power of the test.