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Biomedical subjects

S A Menefee

Publications and source records attributed to S A Menefee.

2 recordsLinked to original sources
PubMed1998

Stress urinary incontinence due to prescription medications: alpha-blockers and angiotensin converting enzyme inhibitors.

BACKGROUND: Several antihypertensive medications affect lower urinary tract function and may cause urinary incontinence. CASE: A 59-year-old woman on doxazosin mesylate for control of her hypertension presented with stress urinary incontinence. Because this drug is known to cause loss of urethral tone leading to stress incontinence in some patients, she was switched to enalapril maleate, an angiotensin converting enzyme inhibitor. Her incontinence improved on the new medication, but she developed a persistent dry cough that continued to cause episodic stress incontinence. Because a persistent cough is a known side effect of angiotensin converting enzyme inhibitors, her medication was changed to a calcium channel blocker, amlodipine besylate. Her cough resolved, and her stress incontinence was no longer a clinical problem. CONCLUSION: Gynecologists should be aware of the unexpected side effects of medications on the lower urinary tract.

Adrenergic alpha-Antagonists↗
PubMed1996

Urinary fistula.

Recent advances in the repair of nonobstetric fistulas include a tendency toward earlier repair attempts, use of ureteral stenting and endoscopic correction, and even the use of laparoscopy for fistula repair. There has also been an increased use of posthysterectomy cystoscopy for early identification of ureteral or bladder injury to prevent later fistula. The current initial success rate for repair of obstetric fistulas in developing countries ranges from 65 to 95%. Now that most obstetric fistulas can be repaired surgically, management of previously nonrepairable fistulas and fistula-associated complications has become a greater focus of concern. Efforts are underway to increase community based obstetric training to prevent obstetric fistulas, and a new obstetric fistula classification has been proposed to emphasize the complications mentioned above.

Developing Countries↗