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Biomedical subjects

S A Partigulov

Publications and source records attributed to S A Partigulov.

18 recordsLinked to original sources
PubMed2004

[Surgical treatment of cancer patients with significant cardiovascular disease].

Twenty patients were operated on for cancer of the lung, stomach, trachea, esophagus, kidney, urinary bladder, rectum, and sigmoid, and tuberculoma of the lung in the presence of significant cardiovascular disease. It has been shown that surgical treatment of cancer patients with significant cardiovascular diseases makes it possible to expand a contingent of radically operated patients who are otherwise doomed to palliative or symptomatic therapy.

Adenocarcinoma↗
PubMed1997

Cardiopulmonary bypass and cell-saver technique in combined oncologic and cardiovascular surgery.

The purpose of this study was to work out an adequate operative technique for patients with malignant tumors who also need open heart surgery or procedures on major blood vessels. We had 8 such patients. In 6 of them, a tumor (3 cases hypernephroid cancer and 3 cases retroperitoneal sarcoma) had grown through the inferior vena cava (IVC) up to the right atrium. Two patients had lung cancer together with severe coronary artery disease. All of these patients were operated on using a heart-lung machine (HLM) and cell saver (CS). In 6 patients the intravascular portion of the tumor was extracted as much as possible through a right atrium approach (in 3 cases a nephrectomy was performed). Two patients had a one-stage coronary artery bypass graft (CABG) and a lobectomy. All of the patients had uneventful postoperative periods and were alive when checked on 1 year after the procedures. During cytological investigation after each operation, tumor cells were found only on the internal surface of the HLM arterial filters with 20 microns holes. We suggest that special cardiovascular devices such as the HLM and CS might be used in borderline situations in oncology without increasing the risk of hematogenous tumor dissemination.

Adult↗
PubMed1991

[Transplantation of the heart-lung complex (the first clinical experience)].

The article deals with experience in the first transplantation of a heart-lung complex in the USSR. The recipient was a 34-year-old male with dilation cardiomyopathy. It was decided to perform the transplantation because the terminal stage of cardiac failure and secondary pulmonary hypertension developed (cardiac index 1.3 l/m, pressure in pulmonary artery 80/50 mm Hg, resistance of pulmonary vessels 10.4 units after Wood). The heart and lung were transplanted from a 19-year-old male who died from a craniocerebral injury. Cyclosporine, metipred , imuran, dopamine in small doses, cardiotonics, and antibiotics were given in the postoperative period; the patient was kept on artificial respiration for 48 hours. For up to 10 days the patient's condition was relatively stable and his consciousness was clear. Bilateral pneumonia developed, however, from which he died on the 12th postoperative day. The article discusses organizational problems and some questions of immunosuppressive therapy, immunological monitoring, and the management of patients after transplantation of a heart-lung complex.

Adult↗
PubMed1991

[Current trends in the development of coronary surgery].

The authors conducted a comparative study of various methods of coronary shunting by means of microsurgical techniques in 240 patients who were operated on for ischemic heart disease. Total myocardial revascularization, including arteries measuring less than 1.5 mm in diameter and vessels in the zones of cardiosclerosis, was found to be more effective than the techniques of shunting of only the affected major branches. The advantages of a mammary-coronary shunt over anauto- logous venous shunt in reconstruction of coronary arteries under unfavourable hemodynamic conditions are demonstrated. It is also shown that multiple bi-mammary-coronary shunting of the branches of the left coronary artery is a promising method.

Adult↗
PubMed1990

[Specific proteinase plasma sorption in surgery with artificial blood circulation].

Cardiosurgery with artificial circulation (AC) is attended with activation of plasma cascade proteolytic systems, which leads to homeostatic disturbances and postoperative complications. AC with the use of specific proteinase plasma sorption in a column with sepharose-immobilized acid-base proteinase inhibitor from human urine prevents activation of proteinase in the plasma. Application of specific plasma sorption facilitates rapid restoration of the plasma protein concentration lowered during AC, improves the course of the postoperative period, and reduces the risk of pulmonary, cardiovascular, and nervous complications.

Adult↗
PubMed1987

[Artificial circulation in microsurgery of the coronary arteries].

Results of 69 aortocoronary bypass operations with the use of microsurgery equipment were analysed. Perfusion was performed under conditions of constant flow, which made it possible to avoid transmissive pulsation, making difficulties for creating microanastomoses. One venous double opening canule was used with no drainage of the left ventricule, which made cannulation easier and created optimal technical conditions for the surgeon. Duration of extracorporeal blood circulation and frequency of intraoperational complications (cardiac failure, myocardial infarction) depended on the operational methods: initial creation of proximal anastomoses resulted in decreased duration of the perfusion, improved protection of myocardium and lower number of complications.

Aged↗
PubMedDate not supplied

[The use of the Autotrans BT 795/P apparatus in surgery with artificial circulation].

The authors assess a possibility of the use of the BT 795/P outfit for aortocoronary shunting in 120 patients with coronary heart disease. Emphasize a considerable decrease in the requirement for donor's blood transfusion to patients undergoing intraoperative blood reinfusion by means of the BT 795/P outfit.

Blood Transfusion, Autologous↗
PubMedDate not supplied

[Variants of procedures of artificial blood circulation and the proteinase activity of the blood].

The use of a "Cell-Saver" technique prevented hyperproteolysis and deletion of proteinase inhibitors in the blood plasma of patients during cardiopulmonary bypass. The technique also improved the course of the postoperative period, decreased the incidence of lung complications and prevented effectively postoperative bleedings. A prognostic value of alpha 1-proteinase inhibitor to trypsin activity ratio in the blood plasma of patients subject of cardiopulmonary bypass surgery has been demonstrated.

Blood Transfusion, Autologous↗