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Biomedical subjects

S A Rizvi

Publications and source records attributed to S A Rizvi.

At least 19 recordsLinked to original sources
PubMed2001

Laser extraction of entrapped leads.

Removing entrapped pacing and defibrillator leads has been greatly simplified by making use of the excimer laser extractor. Sixty-two leads were successfully removed, although where appropriate, portions of the lead remained in place in 10 cases. There were two serious complications, one tear of the superior vena cava during an ICD extraction and one tear of the atrium during an atrial lead extraction. Both were controlled successfully through emergency sternotomy. Although extracting entrapped leads has been much simplified by making use of the laser extractor, the process is not free of serious complications. Those involved in explanting leads should be aware of the outcomes and be prepared for emergent management.

Device Removal↗
PubMed2000

High-energy microwave thermotherapy in patients in urinary retention.

PURPOSE: To study the outcome of high-energy transurethral microwave thermotherapy (TUMT) in patients with obstructive benign prostatic hyperplasia (BPH). PATIENT AND METHODS: Between September 1995 and March 1998, patients presenting with urinary retention secondary to BPH were recruited into the study. Their mean age was 67.2 years (range 50-85 years). The mean catheterization time prior to treatment was 3 months (range 15 days-1 year). Among the 200 patients treated during this period, 30 were high anesthesia risk (American Society of Anesthesiologists Class III/IV). The patients were treated in a single 1-hour session using high-energy (Prostatron 2.5) software, the range of energy transmitted being 111.9 to 214.2 kJ (mean 196.3 kJ). Symptoms were scored according to the International Prostatic Symptom Score (IPSS). The mean prostate volume subjected to TUMT was 59 cc (range 40-149.7 cc). The patients were followed every 3 months with measurements of peak flow rate, postvoiding residual urine volume estimation, and IPSS. RESULTS: Of the 200 patients, 33 were lost to follow-up, 155 were responsive (catheter free with physiologically acceptable peak flow rate), and 12 (7%) were nonresponsive. Only 4 patients (2%) experienced deterioration in their flow rates during the follow-up period of 2 years. They underwent transurethral resection. High-energy thermotherapy resulted in irritative voiding complaints in 80% of patients for 2 to 4 weeks. CONCLUSION: The initial results were encouraging, and the 2-year follow-up has shown appreciable sustainability in the treatment outcome, particularly in patients at high anesthesia risk.

Aged↗
PubMed1998

Outcome of machine-perfused non-heart-beating donor kidneys, not allocated within the Eurotransplant area.

UNLABELLED: Eleven non-heart-beating (NHB) donor kidneys considered vital during machine perfusion (MP), could not be allocated inside Eurotransplant (ET). With the help of ET, five kidneys were transplanted in Karachi and six in Basel. Our goal was to prove that NHB kidneys successfully passing MP viability tests can be transplanted safely. METHODS: Donor age, serum creatinine (some post-mortem) and warm ischaemic time were, respectively, (mean and range): 44 (14-70) years, 137 mumol/l, and 44 (9-80) min. Reasons for refusal were: bold ureter (one), suboptimal flush (one), relatively long hypotensive phase (seven), and donor age of 70 years (two). After 8 h of MP, mean lactate dehydrogenase, intrarenal resistance and alpha glutathione S-transferase were (including range): 556 U/l (range 366-819 U/l), 0.86 mmHg/ml per min (0.41-1.15 mmHg/ml per min) and 1188 micrograms/l (575-2677 micrograms/l), respectively. Mean cold ischaemic time was 45 (range 28-72) h. RESULTS: Two kidneys showed immediate function, and nine showed delayed function. Mean creatinine levels after 1, 3 and 6 months were 295, 200 and 206 mumol/l, respectively. Four patients died for reasons not related to their kidney transplantation. CONCLUSIONS: We claim that MP can successfully assess viability of NHB donor kidneys. The reluctance to accept MP, and judged vital, NHB donor kidneys is not longer justified.

Adolescent↗
PubMed1997

Prediction of renal function recovery in obstructive renal failure due to stones.

Two hundred and thirty-nine patients with renal and ureteric calculi associated with renal failure were evaluated for recovery potential before definitive surgery. Ultrasonography was carried out pre-operatively in all, followed by percutaneous nephrostomy (PCN) as an initial management before definitive surgery. Diethylene triamine penta acetic acid (DTPA) scan was done in 125 patients after percutaneous nephrostomy, findings of pre- operative DTPA scan were correlated with post-operative drop in serum creatinine. Urine pH, urine Na+, initial diuresis, creatinine clearance and serum creatinine were measured serially after 24 hours and then every week for 6 weeks. Patients were re-evaluated with serum creatinine after 3 months of surgery. Ultrasonography was found to be reliable in predicting future recovery of renal functions in 76.5% cases and true obstruction of shorter duration (F4-group) on DTPA scan in 81.9% cases. Urine pH of 6 or less, post-PCN diuresis and natriuresis were good prognostic indicators. PCN was found to be most reliable method of predicting future recovery of renal function after relief of obstruction with 97.8% accuracy.

Adult↗