PubMed Health⌕ Search

Biomedical subjects

S A Siddiqui

Publications and source records attributed to S A Siddiqui.

13 recordsLinked to original sources
PubMed1992

Incidence & immunological profile of multiple myeloma patients.

Multiple myeloma was diagnosed in 84 residents of Jammu & Kashmir between 1984-1988. The data were analyzed for variations of demographic factors, ethnicity and location of residence (urban/rural). The average annual incidence per 100,000 residents was 1.28. The rates for males and females were 2.02 and 0.71 per 10(5) persons/year respectively. The average incidence rate for Muslims was significantly higher than that for Hindus. Urban residents had significantly higher rates than rural population. Highest incidence rate (14.39) was in the age group of 65 yr and above.

Adult↗
PubMed1990

Haemostatic clips and clamps used in surgical neurology with special reference to non ferro magnetic Phynox spring clips by Aesculap.

This paper concerns the historical developments and technical properties of haemostatic devices used in neurosurgery with the exception of coagulation. Therefore there are described haemostatic clips designed for the scalp, clips used on arteries and veins, a clamp for the reduction of the carotid diameter in the neck, and a clamp for closing the venous dural sinuses. Special reference will be made regarding non ferro magnetic Phynox clips by Aesculap.

Hemostasis, Surgical↗
PubMed1986

Cardiovascular effects produced by a combination of d-tubocurarine and pancuronium in dogs.

The effect on the cardiovascular system of a combination of pancuronium (0.048 mg/kg) and d-tubocurarine (0.288 mg/kg) was studied in five conditioned dogs anesthetized with fentanyl. Changes in heart rate, mean arterial pressure, central venous pressure, mean pulmonary artery pressure, pulmonary capillary wedge pressure, stroke volume, cardiac output, systemic vascular resistance and pulmonary vascular resistance were recorded 2, 5, 10, 20, 30, 40 and 50 minutes after administration of the drug combination. Arterial blood samples were assayed for estimation of histamine levels. There was a significant fall in central venous pressure and mean arterial pressure at 2 minutes (p less than 0.05) and a significant rise in heart rate at 2 and 5 minutes (p less than 0.05). These changes were not significant at 10 minutes. There was no significant change in the other parameters measured and no significant release of histamine. It is concluded that the smaller doses of pancuronium and d-tubocurarine used in combination in dogs do not completely attenuate the cardiovascular effects of either drug when used independently, but that the changes are transient and no longer significant at 10 minutes.

Animals↗
PubMed1978

A semi automated procedure for the measurement of 3-methoxy-4 hydroxy mandelic acid.

A semi automated procedure for the determination of 3-methoxy-4-hydroxy-mandelic acid (HMMA) in urine has been evaluated. This procedure offers advantages in simplicity, speed and precision over existing manual techniques which utilize spectrophotometric fluorimetric and gas liquid chromatographic methods. The urine is extracted with ethyl acetate from a highly acidic sample, purified by extraction into acetate buffer and the diazo colour reaction developed. All stages of the procedure are carried out using the Brown and semi-automatic extractor equipped with partition tube. The within and between assay coefficient of variation obtained on pooled freeze-dried urine samples was 6.7% and 7.7% respectively.

Autoanalysis↗
PubMed1976

Laboratory assessment of thyroid disorders - which test should be used?

There are a variety of laboratory investigations which have been used in the assessment of thyroid function and it is obvious that not all of these tests can be used on each occasion. Which, therefore, provides the best diagnostic index? Each test is designed to assess a particular aspect of the thyroid gland and it is often not possible to select a single test as an ideal and exclude the others. The data presented in this paper indicate the advantages of using a combination of various procedures as a screening profile to cover all thyroid abnormalities. The results of several thyroid tests accumulated over the past five years are critically examined to assess their diagnostic value separately and in selected groups. Introduction.

Humans↗
PubMed1973

A comparative study of five laboratory tests for foeto-placental dysfunction in late pregnancy.

Five foeto-placental function tests were studied in parallel in normal and abnormal late pregnancies with a view to establishing which test or tests is most satisfactorily able to identify the mother whose foetus is in danger.A critical examination of the levels in blood serum of two enzymes, placental phosphatase isoenzyme and cystine aminopeptidase, the polypeptide hormone placental lactogen (chorionic somatomammotrophin), and the oestrogen oestriol-17beta is described.A correlation was attempted beween clinical data and the results of the above laboratory analyses and also with the daily urine oestrogen output. The plasma and urine oestriol levels proved generally to be the more useful warning tests in late pregnancy, whilst the plasma cystine aminopeptidase was the least sensitive indicator of foeto-placental dysfunction.

Aminopeptidases↗