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Biomedical subjects

S A Slavin

Publications and source records attributed to S A Slavin.

26 records · Page 2Linked to original sources

An investigation of bacteremia during rhinoplasty.

The rarity of infection after rhinoplasty is not well understood. Despite the apparent low incidence of this complication, many surgeons administered perioperative antibiotics to prevent infection. We studied whether a bacteremia composed of nasal flora can originate during rhinoplasty. Fifty-two health patients admitted for rhinoplasty were studied. Blood and nasal cultures were drawn immediately before operation and blood cultures 5 and 15 minutes after completion of the nasal osteotomies. With the exception of one instance of likely contamination, none of the blood cultures grew microorganisms. Neither local nor systemic infections occurred in any patient. The negative results of this study suggest an exceedingly low incidence of bacteremia during rhinoplasty. For this reason, the value of perioperative antibiotic prophylaxis is questionable.

Adolescent↗

Congenital infiltrating lipomatosis of the face: clinicopathologic evaluation and treatment.

Congenital lipomatosis of the face is characterized by collections of nonencapsulated, mature lipocytes which infiltrate local tissues and tend to recur after surgery. These lesions represent a distinct clinicopathologic entity that has not been previously reported in this location in children. Three children with congenital lipomatosis of the face were treated at the Institute of Reconstructive Plastic Surgery over a 2- to 14-year follow-up period. In each instance, pathologic evaluation by light and electron microscopy revealed similar lesions sharing the following morphologic criteria: (1) nonencapsulated tumors containing mature fat cells, (2) infiltration of adjacent muscle and soft tissue, (3) absence of malignant characteristics, (4) absence of lipoblasts, (5) presence of fibrous elements in conjunction with increased numbers of nerve bundles and vessels, and (6) hypertrophy of subjacent bone. All three lesions recurred after numerous excisions, some of which were extensive. All were benign by histologic examination and remained so for as long as 14 years. Surgical treatment improved the aesthetic appearance of each child despite evidence of tumor persistence. Although these tumors are benign, we recommend an early aggressive surgical approach to control the infiltrative nature of their growth and to improve facial appearance.

Child↗

Microvascular reconstruction of the hand.

For the patient with a demonstrated occlusion in either the major arterial supply of the hand or in the distal digital circulation, modern microsurgery offers an opportunity for reconstruction with restoration of normal flow and sensibility. Observation should not be the mainstay of therapy for digital or upper extremity ischemic symptoms. The surgeon may select from a myriad of sophisticated invasive and noninvasive tests that permit definitive identification of microvascular pathology. Until further improvement in pharmacologic treatment occurs, microsurgery offers the greatest opportunity for correction of these conditions.

Aneurysm↗

Clinical trials of amniotic membranes in burn wound care.

Four test conditions of increasing complexity were used to evaluate the clinical efficacy of amniotic membranes as biologic dressings on donor sites and burn wounds in children. These were the clean-skin donor-site wound, the uncontaminated shallow partial-thickness burn wound, the bed of freshly excised full-thickness wounds, and the granulating surface of colonized burn wounds. The rate of epithelialization under amniotic membranes was the same as that under 5% scarlet red ointment or 0.5% silver nitrate solution dressings. Preservation of a healthy excised wound bed and maintenance of a low bacterial count in contaminated wounds paralleled the experience with human allograft dressings despite technical difficulties and the absence of vascularization of amniotic membrane and its fragile structure. Tentative conclusions are drawn as to the mechanisms by which biologic dressings exert their beneficial effects.

Bandages↗

A new technique for diagnostic peritoneal lavage.

Because of the unique anatomic relationships present in the umbilical ring, peritoneal lavage puncture is recommended at this site, Lacking in subcutaneous fat, adherent to peritoneum, the umbilical ring appears well suited for lavage puncture. As a locus of entry, it eliminates the necessity to incise down to the peritoneum and obviates the usage of epinephrine. Entry into the peritoneal cavity is enhanced by the intimate relationship between skin and peritoneum. Finally, the strength of the inferior portion of the ring, resulting from the fibrosis and scarring of the urachus and both umbilical arteries, vitiates the potential of postpuncture umbilical hernia.

Humans↗