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Biomedical subjects

S A Tayel

Publications and source records attributed to S A Tayel.

2 recordsLinked to original sources

Antimicrobial activity of chloramphenicol in solid dispersion systems.

The effect of solid dispersion techniques on the antimicrobial activity of chloramphenicol has been studied and it was proven that the antimicrobial activity of chloramphenicol is not affected when the drug is present as a coprecipitate with carbowaxes (4.000, 6.000, 12.000), and PVP 11.000 and 40.000) also in fusion systems with these polymers. In contrast, the antimicrobial activity of the drug is enhanced when it is present in the from of a solid dispersion system.

Chloramphenicol

Effect of certain additives on the dissolution rate of chloramphenicol.

A study was conducted on the effect of certain additives on the dissolution rate of chloramphenicol. The effect of adsorbents, natural and synthetic surface active agents, diluents and lubricants was studied. Many of these additives increased the dissolution rate of chloramphenicol from capsules.

Alcohols