Biomedical subjects

S Acevedo de Mendilaharsu

Publications and source records attributed to S Acevedo de Mendilaharsu.

9 recordsLinked to original sources

PubMed1977

[Atrophy of the hippocampus of vascular origin. Clinico-pneumoencephalographic study].

Among 20 patients with symptoms of cerebrovascular insufficiency, dissociation between memory disturbances and cognitive functions, and PEG studies, there were 13 cases showing atrophy of the hippocampus. The neurological and psychological studies included memory functions tests, IQ, and the analysis of language and praxia. Complementary tests included standard EEG records, EEGs obtained with nasopharingeal electrodes and PEG tomography with selective filling of both temporal horns, in order to demonstrate the inner and lower surface of the temporal lobes. The volume of the Ammon horn was reduced in 13 cases. Hippocampal atrophy was unilateral in 11 patients and bilateral in 2. The fact that hippocampal atrophy was demonstrated by PEG studies in 13 out of 20 cases, appears to be highly significant. This clinico-neuroradiological correlation seems to indicate that hippocampal atrophy, following ischemia in the deep distal vertebro-basilar-posterior cerebral territory, disturbs the function of axial structures (Papez circuit or limbic system) apparently leading to the disturbances of memory functions observed in this group of patients.

Adult↗

PubMed1976

[Memory disorders in posterior vertebrobasilar cerebral artery insufficiency].

A clinical and neuropsychological study of 10 vascular patients with signs of circulatory insufficiency in the vertebro-basilar-posterior cerebral territory in whom the dominant symptom was loss of memory with relative idemnity of other intelectual functions is presented. In 5 cases clinical signs of acute infarct in the posterior cerebral artery territories existed in the form of amnesic infarct. The disturbances and the localization of the lesion confirmed by paraclinical examinations (EEG, angiography of the posterior circulation, radioisotope scan) are discussed.

Aged↗

PubMed1975

[Comparative study of the cognitive functions and symbolic order in temporal and centerencephalic epilepsy of long development of difficult therapeutic control].

The paper is centered in the comparative study of three groups of long-term epileptic patients in which therapeutic control is difficult to achieve, by means of several neuropsychological tests evaluating levels of intelligence, memory, language and praxis. Paget's tests of conservation of physical quantities revealed no significant differences in results obtained from the exploration of operative levels between epileptics with right temporal, left temporal or centrencephalic electroencephalographic foci. There is no parallel decrease of operative level when present, and deficit of mnesic functions, which is constantly observed in the three groups and usually evidenced in short-term memory. The graphic representation of projective space (Cube, house), is parallel to operative weakening. No significant relationship between lateralization of focus and graphic performance is observed. Language exploration by means of Benton and Spreen's battery of tests shows distinctly similar results in the three groups of patients. The location of the epileptic focus shows no relevance with respect to language disturbances. The most outstanding pathologic phenomenon is a certain degree of anomia observed in the naming of objects. Its significance is discussed (Slight degree of amnesic aphasia, deficit of evocative memory, or a lexical level in accordance with the operative deficit). The deficit of the repetition of sentences test and in others including a time element should not be ascribed to a specific language deficit. True aphasia was present in only three patients of the left temporal group after prolonged status epilepticus.

Adolescent↗

PubMed1971