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S Andersen

Publications and source records attributed to S Andersen.

135 records · Page 8Linked to original sources
PubMedDate not supplied

Valproate competes with palmitate for binding to serum albumin.

Addition of sodium valproate (VPA) to a buffered solution of human serum albumin (HSA) or to serum reduces binding affinity for palmitate. A maximal pharmacologic VPA concentration, 700 microM, added to a 300-microM albumin solution, reduces the reserve albumin concentration for binding of palmitate by a factor of 0.64. One possible site model explaining these findings may be that VPA competes strongly with one among three palmitate molecules, bound to albumin with high affinity, and induces a weaker displacement of a second palmitate.

Binding, Competitive↗
PubMedDate not supplied

Spread of equine lungworm (Dictyocaulus arnfieldi) larvae from faeces by Pilobolus fungi.

Between 10 and 25% of the Dictyocaulus arnfieldi larvae excreted in faeces from a naturally infected donkey were harvested as infective stages from faecal cultures by means of Pilobolus fungi. The faeces were collected between 24 and 56 hours after drenching the donor animal with Pilobolus spores and kept at 16 +/- 2 degrees C. Most larvae were collected between the 5th and the 8th day of culturing during which period fructification and sporangium discharge also peaked. The sporangia and the adhering larvae were collected in Petri dishes inserted between the faecal mass and a light source. All recovered larvae were viable. A mean larval length of 368 microns (range 312-440 microns) and width of 14.6 microns (range 12-20 microns) was recorded for the infective stage. The method was found suitable for the recovery of infective stages for experimental purposes. The authors suggest that the Pilobolus mechanism play an important part in the spread of equine lungworm infection under field conditions similar to the situation in bovine lungworm (Dictyocaulus viviparus) infection.

Animals↗
PubMedDate not supplied

[Prevalence of lungworm D. arnfieldi (Cobbold 1884) in donkeys in Denmark and in horses in herds together with donkeys (author's transl)].

During a 5 months' period from January to May 1981 faecal samples of 176 donkeys from 59 herds all over the country were examined at the Institute of internal medicine, The Royal Veterinary and Agricultural University, Copenhagen. In addition, the investigation also included 106 horses from 30 of the donkey herds and 34 horses hospitalized with symptoms of dyspnoea and chronic coughing. In all, 87.5% of the donkeys were shown to excrete D. arnfieldi larvae, often in very high numbers, and the larval excretion was the only symptom of lungworm infection. There was no significant correlation between larval excretion and age, sex or herd size. In horses, the frequency of D. arnfieldi infection was approximately the same in the horses from donkey herds and in horses hospitalized due to chronic cough (10.4% and 8.8% resp.). In contrast to the donkeys, the infection in horses was always accompanied by dyspnoea and coughing.

Animal Diseases↗
PubMedDate not supplied

Acroosteolysis of Phalanx III in Danish Landrace pigs. A radiological and histological study.

The herd examined is considered to be a typical representative of Danish pigherds. The investigation shows that acroosteolysis is highly prevalent. As for most pathological conditions in the legs of pigs the condition is concentrated around the bigger of an uneven pair of toes. Frequency and extent of the lesions in the animals are increased with increasing age and with increasing difference in size between the paired toes. Acroosteolysis is caused by vasculitis in the distal vessels followed by osteolysis. During the later development of the condition there is no healing or callus formation in the osteolytic areas, but an extension of the free osseous areas with an apposition of osseous tissue is observed. The clinical manifestations are not specific. The condition is not hereditary, and there are no sex-correlations. The histological appearance is comparable to that of allergic reactions due to e.g. erysipeloid in pigs, and also to allergic acroosteolytic conditions in humans (Raynaud's phenomenon). Therefore, an allergic etiology cannot be rejected.

Animals↗