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S Awazu

Publications and source records attributed to S Awazu.

At least 181 records · Page 10Linked to original sources
PubMed1976

Simple method of hepatic venous blood sampling in the rat.

An improved method of hepatic venous blood sampling by catheterization in rats is proposed and applied to the measurement of hepatic blood flow (HBF) by the continuous ICG infusion method in normal rats and in rats treated chronically with CC1(4). The value of HBF determined by the present method was 0.90 +/- 0.17 (SD) ml/min per g liver under ether anesthesia, which was consistent with the reported values determined by other more complicated methods. The applicability of the present method was also shown in CC1(4) chronic intoxicated rats, to give 0.64 +/- 0.11 ml/min per g liver of HBF.

Animals↗
PubMed1975

Transport of sugars and amino acids in bacteria. XVI. Theory and evaluation of a model for the membrane transport reaction mediated by a single carrier with three binding sites for substrate.

A novel model is presented for bacterial active transport reactions which show a curvilinear Eadie-Hofstee plot and negative homotropic cooperativity in the kinetics of substrate uptake. Various models of a single carrier with multi-binding sites for substrate were constructed and examined theoretically. The fit of these models with experimental data on the kinetics of branched chain amino acid transport reactions were tested by iterative computation using the non-linear least square method. The transport model which fitted the experimental data best consisted of a single carrier with three binding sites for substrate in which one of the substrate-carrier complexes, CSS, is not active in translocating substrate across the cytoplasmic membrane. The mechanism of homeostatic regulation of the intracellular concentration of amino acids by active transport systems is discussed on the basis of this transport model.

Binding Sites↗