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Biomedical subjects

S B Bavdekar

Publications and source records attributed to S B Bavdekar.

At least 19 recordsLinked to original sources

Effect of deferiprone on urinary zinc excretion in multiply transfused children with thalassemia major.

A prospective multi-centric study was conducted to determine if iron-chelating agent deferiprone also chelates zinc. Twenty four-hour urinary zinc levels were compared in multiply transfused children with thalassemia major not receiving any chelation therapy (Group A, n = 28), those receiving deferiprone (Group B, n = 30) and age and sex-matched controls of subjects in Group B (Group C, n = 29) by a colorimetric method. The 24-hour mean urinary excretion of zinc was significantly higher in Group B than in the other two groups indicating that deferiprone chelates zinc.

Blood Transfusion↗

Congenital factor VII deficiency.

A 1(1/2)-month-old baby with seizures, lethargy and refusal of feeds was diagnosed to have intracranial hemorrhage due to factor VII deficiency. MRI also demonstrated the unusual presence of a hemorrhagic infarct. The case underscores the importance of carrying out neuroimaging and appropriate hematological studies even in the absence of obvious external bleeding. Hypothesis for increased propensity for intra-cranial hemorrhage is discussed.

Blood Component Transfusion↗

Study of infant feeding practices: factors associated with faulty feeding.

KEM Hospital, Mumbai was recognized as a 'baby-friendly' hospital on the basis of adherence to the 'Ten steps to successful breastfeeding', a decade ago. This study was undertaken to determine the sustainability of the programme in terms of feeding practices undertaken by the mothers on the basis of advice given to them. A total of 92.11 per cent of the infants up to 6 months of age received exclusive breastfeeding. Timely complementary feeding rate was 95 per cent. Thus interventions used in the programme seem sustainable.

Breast Feeding↗

Viscerohepatodiaphragmatic interposition (Chilaiditi's syndrome) in a child.

Viscerohepatodiaphragmatic interposition or Chilaiditi's syndrome is a rare congenital anomaly characterised by subphrenic displacement of the intestine resulting from a congenital anomaly of the hepatic ligaments. A six-year-old asymptomatic girl was screened for tuberculosis as her father was suffering from sputum-positive pulmonary tuberculosis. The chest radiograph showed normal lung fields, but a gaseous shadow was seen beneath the right dome of the diaphragm, which was confirmed, to be a case of Chilaiditi's syndrome on abdominal radiographs and ultrosonography. Although initially thought to be a benign condition, Chilaiditi's syndrome has been cited to be an important cause of acute abdomen. It is, therefore, important that the clinicians are aware of the condition when treating such a child.

Child↗

Necrotizing myelitis in an immunocompetent child: a case report with review of literature.

A few cases of necrotizing myelitis have been reported in adults since its first description in 1973. No case has been described in the pediatric age group. A 12-year-old boy, who presented with acute flaccid paraplegia, loss of sphincter control and sensory loss showed features suggestive of necrotizing myelitis on magnetic resonance imaging. Investigations carried out could not reveal a specific etiological or pre-disposing factor. No clinical improvement occurred despite the therapy.

Child↗

Mycotic aneurysm: an uncommon cause for intra-cranial hemorrhage.

Intra-cranial mycotic aneurysms due to an infective process elsewhere in the body constitute an uncommon cause of intra-cranial hemorrhage. The condition carries a grave prognosis. Mycotic aneurysms secondary to infective endocarditis (IE) rarely occur in children. This communication describes a seven-year-old girl who presented with fever and neurological abnormalities. She was diagnosed to have a mycotic aneurysm secondary to IE. Digital subtraction angiography (DSA) confirmed the diagnosis, delineated anatomical details and later detected the complete resolution of the aneurysm following conservative management with intravenous antimicrobial agents.

Aneurysm, Infected↗

Neonatal Bartter syndrome.

A case of neonatal Bartter syndrome is reported. The baby born pre-term following a pregnancy complicated by polyhydramnios, presented at 7 months of age with failure to thrive, gastroenteritis and facial dysmorphisms. An unusual feature was the absence of the classical biochemical abnormality of hypochloremic alkalosis early in the course of the disease. Metabolic acidosis was the initial manifestation at 5 weeks of age. Awareness of this presentation is important to avoid delay in diagnosis and treatment.

Administration, Oral↗

Primary intraventricular haemorrhage: a rare presenting feature of arteriovenous malformation in children.

Two cases of arteriovenous malformation (AVM) of the brain presented with primary intraventricular haemorrhage in eleven and thirteen years old children, respectively. The cases responded favourably to therapy with steroids, anti-epileptic drugs and therapeutic embolisation in the former. Though such presentation accounts for 3% of the adult intracranial bleeds secondary to AVM rupture, the same has not been reported in children.

Adolescent↗

Infantile hemangioendothelioma.

Primary hepatic tumors are uncommon in children and account for only three per cent of the tumors in children. Infantile hemangioendothelioma is a rare benign hepatic tumor arising from mesenchymal tissue. Most of the cases present before six months. An unusual presentation and progression of infantile hemangioendothelioma is reported in a 19-month-old female child. The diagnosis was arrived at by radiological and histopathological examination. The patient underwent excision surgery, following which made an uneventful recovery. On follow-up at six months, patient was asymptomatic with no evidence of recurrence.

Female↗

Selective testosterone secreting adrenocortical carcinoma in an infant.

Adrenocortical carcinoma in children is a rare tumor of adrenal gland. An infant presented with signs of virilization due to selective testosterone hypersecretion. Diagnosis was established with the help of the computerized tomographic scan and histopathological examination. Following adrenalectomy patient made uneventful recovery and six months later does not have any clinical or laboratory evidence of recurrence or metastasis.

Adrenal Cortex Neoplasms↗

Thyroiditis as a presenting feature of mumps.

Thyroiditis complicating mumps is rare and occurs 1 week after the parotitis. A 9-year-old boy with a history of contact with a case of mumps presented with thyroid swelling. Thyroid scan showed a diffusely reduced uptake. The aspiration cytology showed lymphocytic thyroiditis. Thyroid function tests were normal and antithyroid antibodies were absent. Parotitis occurred 12 days after the onset of thyroiditis.

Child↗