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Biomedical subjects

S B Eaton

Publications and source records attributed to S B Eaton.

10 recordsLinked to original sources
PubMed1992

Humans, lipids and evolution.

The genetically ordered physiology of contemporary humans was selected over eons of evolutionary experience for a nutritional pattern affording much less fat, particularly less saturated fat. Current dietary recommendations do not accord exactly with those generated by an understanding of prior hominoid/hominid evolution. Similarly, widely advocated standards for serum cholesterol values fail to match those observed in recently studied hunter-gatherers, whose experience represents the closest living approximation of "natural" human lipid metabolism. The evolutionary paradigm suggests that fats should comprise 20-25% of total energy intake, that the ratio of polyunsaturated to saturated fat should exceed 1.0, and that total serum cholesterol levels should be below 150 mg/dL (approximately 4 mM/L).

Animals↗
PubMed1991

Calcium in evolutionary perspective.

The nutritional requirements of contemporary humans were almost certainly established over eons of evolutionary experience and the best available evidence indicates that this evolution occurred in a high-calcium nutritional environment. The exercise and dietary patterns of humans living at the end of the Stone Age can be considered natural paradigms: calcium intake was twice that for contemporary humans and requirements for physical exertion were also greater than at present. Bony remains from that period suggest that Stone Agers developed a greater peak bone mass and experienced less age-related bone loss than do humans in the 20th Century.

Agriculture↗
PubMed1991

Primitive health.

Explore the source record for details and available documents.

Exercise↗
PubMed1976

Spontaneous internal drainage of pancreatic pseudocysts.

Six cases are reported in which spontaneous internal drainage between a pancreatic pseudocyst and the alimentary tract became established. In each instance the communication was demonstrated radiologically. The clinical circumstances and radiographic features of these cases are described, and the existing literature pertaining to this phenomenon is reviewed.

Acute Disease↗
PubMed1975

Results of hypotonic duodenography in the diagnosis of pancreaticoduodenal cancer.

Hypotonic duodenography has become a well accepted procedure for diagnosing pancreaticoduodenal cancer. In order to provide further data about the accuracy of this examination, 170 patients were reviewed who were suspected of having this disease and whose duodenogram diagnosis was later confirmed or disproved by surgery, autopsy, or clinical follow-up. The correct diagnosis was made in 158 patients (over-all accuracy of 93%). Of 31 ultimately proved pancreaticoduodenal cancers, 24 were correctly identified (specific accuracy of 77%). For 27 patients a positive diagnosis of pancreaticoduodenal cancer was made, and 24 of these later proved to have this disease (positive accuracy of 89%). For 110 patients, a negative diagnosis was made, and 103 of these proved to be free of pancreaticoduodenal cancer (negative accuracy of 94%).

Bile Duct Neoplasms↗
PubMedDate not supplied

Putting the wrong fuel in the tank.

Three recent observations when considered together indicate means whereby the health of Western countries could be improved and certain diseases still rare in developing countries avoided. The first is the recognition that many of the commonest chronic disorders in more economically developed countries are characteristic of modern Western lifestyles; the second is that these disorders can be considered to be manifestations of maladaptation to a new environment; and the third is the knowledge now available of the types of environment to which man has, through evolution, adapted.

Diet↗