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Biomedical subjects

S B Gay

Publications and source records attributed to S B Gay.

At least 19 recordsLinked to original sources

Processes involved in reading imaging studies: workflow analysis and implications for workstation development.

Software development for imaging workstations has lagged behind hardware availability. To guide development and to analyze work flow involved in interpretation of cross-sectional imaging studies, we assessed the cognitive and physical processes. We observed the performance and interpretation of body computed tomography (CT) scans and recorded the events that occurred during this process. We studied work flow using a bottleneck analysis. Twenty-four of a total of 54 cases (44%) involved comparing the images with those of prior scans. Forty-seven of 54 scans (87%) were viewed using windows other than soft tissue, or compared with precontrast scans. In 46 cases (85%), the interpretation stopped to return to a previous level for review. Measurement of lesions was performed in 24 of 54 (44%) cases, and in 15 (63%) of these cases, measurements were taken of lesions on old studies for comparison. Interpretation was interrupted in 14 of 54 cases (26%) by referring clinicians desiring consultation. The work flow analysis showed film folder retrieval by the film room to be the bottleneck for interpretation by film. For picture archiving and communication system (PACS) reading, the CT examination itself proved to be the bottleneck. We conclude that workstations for CT interpretation should facilitate movement within scans, comparison with prior examinations, and measuring lesions on these scans. Workstation design should consider means of optimizing time currently not used between interpretation sessions, minimizing interruptions and providing more automated functions currently requiring physician interaction.

Cross-Sectional Studies

Attitudes of radiology residents toward personal computing: results of survey.

RATIONALE AND OBJECTIVES: The authors' purpose was to evaluate radiology residents' assessment of their own computer skills for potential development of computer training in a residency curriculum. METHODS: The authors conducted a survey to evaluate the attitudes of radiology residents concerning personal computing. Surveys were completed by 136 radiology residents from six academic institutions. RESULTS: Sixty percent of residents surveyed considered themselves to be computer literate and 93% would like further computer training. Fifty-six percent had a computer at home and 9% had a laptop. Almost all residents had access to a computer at work. Word processing and medical literature searches were the most common computer tasks performed by residents. Image processing was the least common task performed. Although all hospitals surveyed were connected to the Internet, only 26% of residents used the Internet and 14% used Internet teaching files. Most residents expressed a preference for self-paced, on-line evening training sessions. CONCLUSION: Most radiology residents believed they possessed adequate computer skills. This proportion has markedly increased over that found in previous surveys. Radiology residents desire and could likely benefit from computer training included as part of the residency curriculum.

Attitude of Health Personnel

Lateral pharyngeal fat pad pressure during breathing in anesthetized pigs.

It has been hypothesized that the pressure in tissues surrounding the upper airway is one of the determinants of the size and shape of the upper airway. To our knowledge, this pressure has not been measured. The purpose of this study was to test whether the pressure in a tissue lateral to the upper airway, the lateral pharyngeal fat pad pressure (Pfp), differs from atmospheric and pharyngeal pressures and whether it changes with breathing. We studied six male lightly sedated pigs by inserting a transducer tipped catheter into their fat pad space by using computerized tomographic scan guidance. We measured airflow with a pneumotachograph attached to a face mask and pharyngeal pressure with a balloon catheter. Pfp differed from atmospheric pressure, generally exceeding it, and from pharyngeal pressure. Pfp correlated positively with airflow and with pharyngeal pressure, decreasing during inspiration and increasing during expiration. Changes in Pfp with ventilation were eliminated by oropharyngeal intubation. We conclude that Pfp differs from atmospheric and pharyngeal pressures and that it changes with breathing.

Adipose Tissue

Lateral pharyngeal fat pad pressure during breathing.

The purpose of this study was to test whether pressure in tissue lateral to the upper airway, the lateral pharyngeal fat pad, differs from atmospheric and pharyngeal pressure and whether it changes with breathing. We studied five male pigs by inserting a transducer-tipped catheter into their fat pad space using computed tomography (CT) scan guidance. We measured airflow with a pneumotachograph attached to a face mask and pharyngeal pressure with a balloon catheter. Fat pad pressure correlated positively with airflow and with pharyngeal pressure, decreasing during inspiration and increasing during expiration. Pressure in the fat pad differed from atmospheric pressure, generally exceeding it, and from pharyngeal pressure. We conclude that lateral pharyngeal fat pad pressure differs from atmospheric and pharyngeal pressure and that it changes with breathing.

Adipose Tissue

Focal liver disease: comparison of breath-hold T1-weighted MP-GRE MR imaging and contrast-enhanced CT--lesion detection, localization, and characterization.

PURPOSE: To compare breath-hold T1-weighted magnetization-prepared gradient-echo (MP-GRE) magnetic resonance (MR) imaging with contrast material-enhanced computed tomography (CT) in the assessment of focal liver disease. MATERIALS AND METHODS: The MR and CT images obtained in 64 patients with focal liver disease were reviewed by six independent reviewers in a randomized, blinded fashion. Sets of axial T1-weighted MP-GRE images, three-plane (a compilation of axial, sagittal, and coronal) T1-weighted MP-GRE images, and contrast-enhanced CT scans were analyzed. T2-weighted spin-echo (SE) MR images were also compared with CT scans. RESULTS: Lesions were detected, localized, and characterized more accurately and generally with greater confidence with three-plane T1-weighted MP-GRE imaging than with CT (P < .01). Axial T1-weighted MP-GRE imaging was also superior (P < .05) to CT (although slightly less superior than three-plane imaging) except in the characterization of specific lesions, where both techniques were equal. T2-weighted SE MR imaging and CT were about equal. CONCLUSION: Lesion detection, localization, and characterization are performed more accurately and confidently with breath-hold T1-weighted MP-GRE imaging than with contrast-enhanced CT, particularly when breath-hold images are obtained in three planes.

Contrast Media

Detection and estimation of the volume of pneumothorax using real-time sonography: efficacy determined by receiver operating characteristic analysis.

OBJECTIVE: The purpose of this study was to determine the efficacy of real-time sonography for the detection and estimation of the volume of pneumothorax using receiver operating characteristic (ROC) analysis in 27 patients evaluated by five radiologists using previously described sonographic findings. MATERIALS AND METHODS: Bilateral chest sonograms were obtained in 27 patients after we performed 26 needle biopsies of the lung and two transcostal biopsies of lesions at the dome of the liver. Thirteen unilateral pneumothoraces were found on radiographs done at the time of the sonograms. The sonograms were recorded on videotape and later viewed by five blinded readers who scored each hemithorax independently as to the likelihood and size of pneumothorax. From these interpretations we were able to calculate ROC curves and standard accuracy statistics for each observer and for pooled data. The results were correlated with the findings on chest radiographs, which were used to verify the diagnoses. RESULTS: The area under the ROC curves ranged from 0.63 to 0.79 in detecting any pneumothorax. The area under the ROC curve derived by pooling readers and hemithoraces using the jackknife method was 0.73. The average sensitivity of the five observers fro pneumothorax was 73%, the specificity was 68%, and the negative and positive predictive values were 89% and 40%, respectively. No significant correlation was found between readers' estimates of pneumothorax size made on the basis of sonographic findings and actual size as ascertained from chest radiographs. CONCLUSION: Real time sonography is useful to localize known pneumothorax but cannot be used to exclude the diagnosis. Moreover, sonography has a significant false-positive rate and is of no use in estimating the volume of a pneumothorax.

Algorithms

Current status of residency programs: survey of program directors.

RATIONALE AND OBJECTIVES: This survey was compiled to provide current data on the structure and content of radiology residency programs and the role of the residency program director. METHODS: A survey, created in electronic form and on paper, was distributed to all United States academic, private, and military radiology residency program directors. RESULTS: Of the 202 survey forms distributed, 168 (83%) were completed and returned. Eighty percent of respondents support national curriculum guidelines, but most do not favor national curriculum requirements. About half (53%) of programs spend 6 months in "view box" nuclear medicine; others provide some experience by lectures and on-call time. Most programs (60%) relieve residents of some call during the senior year. Some programs (28%) allow seniors time away from clinical duties to study for the oral board exam, and 17% permit time away to study for the written boards. Seventy-eight percent of programs have had a "problem resident," and 47% have asked a resident to leave the program. Directors' most frequently expressed concern was threat of diminished residency numbers due to decreased funding.

Attitude of Health Personnel

Computed tomography appearance of the prostatic fossa following radical prostatectomy.

RATIONALE AND OBJECTIVES: We assessed the value of postsurgical computed tomography (CT) in detecting locally recurrent prostatic carcinoma and determined the most effective CT findings. METHODS: We studied 13 patients with recurrent disease (prostate specific antigen [PSA] > 0.4 ng/ml) and 11 patients with no evidence of recurrence (PSA < 0.3 ng/ml). Pelvic CT scans were independently interpreted by four readers who were unaware of patient status. Readers measured tissue volume in the prostatic fossa and evaluated each scan for the presence of six potentially discriminating criteria. We determined sensitivity and specificity and developed mean and pooled receiver operating characteristic (ROC) curves for each criterion and for overall rating. RESULTS: The respective mean ROC curves, sensitivity, and specificity for each criterion were as follows: irregular tissue margins = .50, .67, and .32; inhomogeneous tissue density = .35, .76, and .11; asymmetric residual seminal vesicles = .68, .86, and .16; fat infiltration around seminal vesicles = .67, .69, and .43; infiltration of perirectal fat = .60, .71, and .40; and margins of the levator ani = .50, .78, and .09. The overall rating of whether a scan was normal or reflected recurrent cancer was .56, .75, and .32. Mean tissue volume in the prostatic fossa was 15.01 cm3 for the positive cases and 11.06 cm3 for the negative cases (p < .05), but because of a large overlap, this difference was not practically significant. CONCLUSION: CT scanning is not an effective technique for detecting recurrent prostate malignancy. Normally, there is a moderate amount of soft tissue in the prostatic fossa postoperatively that should not be confused for malignancy.

Adenocarcinoma

Hiring preferences of diagnostic radiology groups: results of a 1994 survey.

RATIONALE AND OBJECTIVES: We surveyed diagnostic radiology group preferences and considerations in hiring radiologists and compared these findings with those of a survey performed in 1990. We sought to identify changes in hiring practices that might have occurred because of socioeconomic changes. We also sought to identify features of job candidates that make them more attractive to hiring groups. METHODS: One hundred surveys were mailed to a stratified random sample of diagnostic radiology groups identified by the American College of Radiology. We solicited information on the importance of various attributes and the level of experience of a candidate, the fellowship training considered most desirable, and the effect of changes in the health care socioeconomic environment. The responses were weighted by group size and geographic location to estimate what results might have been obtained if we had surveyed all groups in the United States. RESULTS: Seventy-five groups returned the survey. The two most important factors in choosing a candidate were motivation and radiologic knowledge. The fellowships that groups that were hiring considered to be the most desirable were body imaging, neuroradiology, and angiography/interventional radiology. Groups overwhelmingly preferred recent training over long experience. CONCLUSION: Fellowship training increases a candidate's marketability, but the two factors that hiring groups consider the most important are motivation and radiologic knowledge.

Clinical Competence

Enlargement of the lateral pharyngeal fat pad space in pigs increases upper airway resistance.

Because the upper airway is partially enclosed in a rigid boundary, enlargement of soft tissue structures within this boundary could narrow the airway. The purpose of this study was to determine whether enlargement of the soft tissue space in the region of the lateral pharyngeal fat pad would increase pharyngeal resistance and narrow the retropalateal upper airway. In five young male anesthetized pigs, we inserted balloon occlusion catheters in the lateral pharyngeal fat pad under computerized tomographic scan guidance. We measured pharyngeal resistance with a pharyngeal catheter and a tightly fitting face mask before and after inflation of the balloons. We also measured pharyngeal airway cross-sectional area before and after inflation of the balloons. In all pigs, balloon inflation significantly increased pharyngeal resistance and significantly decreased the area of the retropalateal airway. We conclude that enlargement of the soft tissue space in the region of the lateral pharyngeal fat pad increases pharyngeal resistance and narrows the retropalateal airway in anesthetized pigs.

Adipose Tissue

Evaluation of a breast biopsy phantom for learning freehand ultrasound-guided biopsy of the liver.

RATIONALE AND OBJECTIVES: We evaluated whether a breast biopsy phantom device would aid in the development of skills in freehand ultrasound liver biopsy. METHODS: Three radiologists who were inexperienced in freehand biopsy of the liver were observed. Each radiologist was timed and scored during attempts to biopsy lesions created in a beef liver. The time required for biopsy and the success of each pass was recorded. A commercially available breast biopsy phantom was then used by each of these radiologists during two 20-min practice sessions. Posttraining testing on the beef liver was performed in the same manner as pretraining testing. RESULTS: Freehand biopsy practice using the breast biopsy phantom resulted in a reduction in the mean time required for biopsy from 32 to 17 sec. Each of the three subjects reduced the mean time required for successful biopsy after training using the breast biopsy phantom. The total number of lesions missed was reduced from 14 of 43 to 0 of 45. CONCLUSION: Practice using the ultrasound breast biopsy phantom improves performance in freehand ultrasound biopsy of the liver.

Animals

MR imaging of the liver: breath-hold T1-weighted MP-GRE compared with conventional T2-weighted SE imaging--lesion detection, localization, and characterization.

PURPOSE: To compare breath-hold T1-weighted magnetization-prepared gradient-echo (MP-GRE) imaging with conventional T2-weighted spin-echo (SE) imaging in evaluation of focal liver disease. MATERIALS AND METHODS: Images of 68 patients evaluated for focal liver disease were reviewed. Five sets of images were analyzed: axial, sagittal, and coronal breath-hold T1-weighted MP-GRE images, axial T2-weighted SE images, and a compilation of axial, sagittal, and coronal (three-plane) T1-weighted MP-GRE images. Lesion signal intensity (SI) and signal difference-to-noise (SD/N) ratios were calculated. RESULTS: Lesions were detected, localized, and characterize more accurately (P < .05-.001) and with greater confidence on three-plane T1-weighted MP-GRE images than on almost all single-plane images. Mean SI ratios of nonsolid and solid lesions on MP-GRE and SE images were significantly different at all lesion sizes; mean SD/N ratio was significantly different only for large lesions. CONCLUSION: Lesion detection, localization, and characterization can be accurately and confidently performed with three-plane T1-weighted MP-GRE breath-hold imaging, potentially obviating conventional T2-weighted SE imaging.

Artifacts