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Biomedical subjects

S B Hameroff

Publications and source records attributed to S B Hameroff.

9 recordsLinked to original sources

Eyelid imbrication. An unrecognized cause of chronic ocular irritation.

BACKGROUND: Eighteen patients with chronic ocular irritation were examined over a 3-year period. All patients demonstrated papillary conjunctivitis and, occasionally, tarsal ulcers. Six also had floppy eyelid syndrome. Underlying every patient's symptoms was the overriding or imbrication of a lax upper eyelid on an often equally lax lower eyelid, allowing lower eyelid lashes to chronically rub the upper eyelid tarsal conjunctiva. METHODS: Chronic ocular irritation in five patients was managed with ocular lubricants. Two of these patients had floppy eyelid syndrome and required nightime shielding for nocturnal eyelid eversion. Thirteen patients underwent eyelid surgery to correct the overriding upper eyelid. Surgical procedures included full-thickness upper eyelid wedge resection, lateral canthal tendon plication, and lower eyelid horizontal shortening, using a tarsal strip procedure. RESULTS: Follow-up averaged 2.5 years. Symptomatology was adequately controlled in all patients. In addition to the five patients who received medical treatment for their symptoms, two with complicated ocular problems required continued ocular lubrication after surgery. Seven patients were successfully treated with eyelid shortening procedures and lateral canthal tendon plication. The remaining six patients underwent a variety of additional eyelid surgeries. All patients undergoing surgery had complete resolution of eyelid imbrication. CONCLUSIONS: Eyelid imbrication is a previously unrecognized cause of chronic ocular irritation. In this condition, eyelid laxity causes the upper eyelid to override the lower eyelid, allowing the lower eyelid to chronically rub and chafe the upper eyelid tarsal conjunctiva. In some cases, symptoms can be managed medically. More often, surgical intervention is required to correct eyelid laxity and prevent overriding of the upper eyelid.

Aged↗

Spasm of the near reflex.

Four patients with spasm of the near reflex are described. This entity is characterized by transient attacks of convergence, accommodation, and miosis, and is usually seen in young individuals as a functional disturbance. This disease has to be differentiated from other horizontal gaze disturbances, including sixth nerve palsy, divergence paralysis, and insufficiency. Despite extensive investigations, no central nervous system disease was found.

Accommodation, Ocular↗

Angioid streaks in pituitary tumor.

The diagnosis of angioid streaks on fundus examination allows the examiner to focus on a limited number of commonly associated conditions, such as pseudoxanthoma elasticum, Paget's disease, and sickle cell disease. There have been sporadic reports of pituitary tumors associated with angioid streaks. This is the first case report of pituitary tumor associated with angioid streaks. This is the first case report of pituitary tumor associated with angioid streaks documented by fluorescein angiography, EMI scan, and histopathologic diagnosis of the tumor, and also in which pseudoxanthoma elasticum was ruled out, both clinically and by a negative skin biopsy.

Adenoma↗

Anterior segment ischemia in temporal arteritis.

Anterior segment ischemia is perhaps the most rare ocular manifestation of temporal arteritis. We described a 73-year-old woman with anterior segment ischemia in the course of temporal arteritis. Early recognition of the syndrome and treatment with high doses of steroids led to visual recovery in the involved eye.

Aged↗

Ocular bobbing.

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Adolescent↗

Ocular bobbing.

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Adolescent↗