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S B Holt

Publications and source records attributed to S B Holt.

17 recordsLinked to original sources
PubMed1995

Hyperglycemia and non-enzymatic glycation of serum and tissue proteins in chickens.

The objectives of these studies were to determine whether elevated plasma glucose concentrations in broiler breeder chickens (200-250 mg/dl) can result in the non-enzymatic attachment of glucose to serum proteins (fructosamine) and eventual cross-linking of tissue proteins (basement membrane thickness), and to investigate the effects of a factor that may influence this cross-linking process. In response to feeding the satiety factor calcium propionate (CaP, 1.7%), plasma glucose and fructosamine concentrations were increased (P < 0.05) from 1 to 9 weeks of age, whereas concentrations of plasma glucose and fructosamine in feed-restricted chicks were reduced for the first 7 weeks after hatch. In a second study, the age-related increase in kidney capillary basement membrane thickness was prevented (P < 0.05) by feeding the cross-linking inhibitor aminoguanidine (AG, 800 ppm) to 30-week-old broiler breeder hens for 34 weeks. The results from these studies suggest that concentrations of plasma glucose in chickens may, in fact, be exerting long-term detrimental effects on tissue proteins, which can be ameliorated by factors that limit the cross-linking reaction.

Administration, Oral↗
PubMed1981

Pseudopseudohypoparathyroidism with lymphoedema and abnormal dermatoglyphics.

This paper describes a woman with pseudopseudohypoparathyroidism (PPHP) who had intractable lymphoedema and also abnormal dermatoglyphics. The findings were quite distinct from those in two previously reported cases of pseudohypoparathyroidism (PHP). Dermatoglyphics may prove useful in the diagnosis of PPHP but may also provide a clue to the factors which distinguish PPHP from PHP.

Adult↗
PubMed1977

Absence of triradius d on the palms of normal people.

Absence of the digital triradius d is a very rare phenomenon, previously only reported in abnormal XXXXY males. During the past few years the anomaly has been found on the palms of three normal females, namely a young English woman and two sisters in the Nicobar Islands in the Indian Ocean. These cases are described and illustrations of the palmar dermatoglyphics presented. The occurrence of such a rare phenomenon in two sisters suggests that it is genetically determined.

Adolescent↗
PubMed1975

The hypothenar radial arch, a genetically determined epidermal ridge configuration.

A radial arch in the hypothenar area of the human palm is an uncommon ridge arrangement. It is associated with an ulnar triradius and no axial triradius is present. The configuration generally occurs on right hands but is sometimes found on both hands. The frequency in the few European populations studied and in one Canadian sample varies from 0.2 per cent to over 2 per cent of persons. Hypothenar radial arches have also been reported in patients with abnormal sex chromosomes but are not specific to any karyotype. Two families are described in which nearly related persons have hypothenar radial arches. They provide the first evidence that the pattern is inherited. In one family three out of six sibs have radial arches in the hypothenar area and so have two out of three children of one of them. In the other family a pair of identical twins and their mother have hypothenar radial arches. It is suggested that, from the information available, inheritance is probably due to a recessive gene.

Canada↗
PubMed1975

Polydactyly and brachymetapody in two English families.

Two new pedigrees of polydactyly associated with brachymetapody are discribed. In one the two defects occur in different members of the family, while in the other both occur in the same individuals. Both anomalies appear to be inherited as dominants, the polydactyly showing incomplete manifestation.

Adult↗
PubMed1973

Dermatoglyphics.

Explore the source record for details and available documents.

Dermatoglyphics↗
PubMedDate not supplied

Dermatoglyphics in Prader-Willi syndrome.

The finger-, palm-and sole-prints of thirteen patients with Prader-Willi syndrome have been analysed. Some information has also been obtained from another case. The topological classification has been used for describing palms and soles. Frequencies of finger pattern types, data on finger ridge-count and maximal atd angles are included. Relevant published data has also been considered in making assessments. It is concluded from the evidence available that the dermatoglyphics of patients with the syndrome differ little, if at all, from those of the normal population. Pattern intensity on hands, and particularly feet, is low. Dermatoglyphics, therefore, are not a useful criterion in the diagnosis of the syndrome.

Adolescent↗