A fatal case of paraquat poisoning in a Nigerian.
A fatal case of paraquat poisoning in an adolescent girl is reported. Death resulted from respiratory failure because of extensive interstitial and intra-alveolar fibrosis.
Biomedical subjects
Publications and source records attributed to S B Lagundoye.
A fatal case of paraquat poisoning in an adolescent girl is reported. Death resulted from respiratory failure because of extensive interstitial and intra-alveolar fibrosis.
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The sinographic appearances in 18 long bones of 14 consecutive patients with sickle-cell anaemia and chronic haematogenous osteomyelitis were studied prospectively; the observed features were compared with the plain radiographic and operative findings. Four sinographic patterns were noted: (1) infected bone cavities with or without sequestra; (2) extensive soft-tissue tracks, alone or in association with infected bone cavities; (3) narrow, wavy intramedullary tracks; (4) short sinus tracks in the soft tissue. Plain films were of no value in demonstrating the presence and extent of soft-tissue and narrow intramedullary tracks; they failed to show infected bone cavities in four instances because of very sclerotic bone. The sinographic features correlated well with the operative findings and contributed significantly to the choice of definitive treatment in 13 out of the 18 bones.
The development of a basic X-ray service in a rural community in southwestern Nigeria is reviewed over a period of 5 years. Of the 3,278 examinations done during this period, chest X-rays constituted 56%. Most of the other examinations were requested on account of trauma of upper and lower extremities: 42 and 43%, respectively. Injuries to the elbow region constituted half of the X-rays for the upper extremities. There was an early upsurge of attendance for all X-rays reaching its peak at the first 2 years of the project, but a stable state was soon established within the subsequent 3 years. The non-chest examinations remained equally divided between the years under review. It is estimated that the introduction of the X-ray service has saved the community some 6,600 working days or 18 years in the 56-month period. This estimate excludes transportation for the accompanying relatives.
A review of 33 fistulograms in a four-year study is presented. Four types of communicating tracts have emerged: single (58%), branched (18%), fistulous abscess (15%) and compound (9%). This classification has formed the basis of selection of operative treatment in all the cases. Diminished lumbo-sacral angle was also found in most of the anal fistula cases and this establishes a possible association between the pathology of anal fistula and the low back syndrome.
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After studying two rural communities with varing endemicity of urinary schistosomiasis by total cross-sectional population survey, a stratified sample was obtained using defined criteria. Plain X-ray abdomen and intravenous pyelogram were carried out on the sample. Findings on plain X-ray of the abdomen, using the usual parameters of psoas and kidney shadows in the Nigerian, indicate that the two communities studied are similar but urinary calculi and urinary tract distortion are significantly more prominent in the community with the higher endemicity of urinary schistosomiasis.
The radiographs of twenty-five patients (eight males, seventeen females) with histologically proven craniofacial fibrous dysplasia were analyzed. The lesions could be classified into six radiologic types: (1) peau d'orange, (2) whorled plaquelike, (3) diffuse sclerotic, (4) cystlike (multilocular or unilocular), (5) pagetoid, and (6) chalky types. The peau d'orange type was by far the most common (40 per cent) followed by the plaquelike (20 per cent, cystlike (16 per cent), and sclerotic (12 per cent). Most of the patients were young, with 60 per cent being underthe age of 20 years and 96 per cent under the age of 40 years.
In Nigeria, tuberculosis of the spine remains an important medical problem in the diagnosis and management of which radiology plays an invaluable role. The present study reviewed sixty-nine cases seen in 1966-1972 at the University College Hospital, Ibadan, Nigeria. The possible radiological classification of the disease was grouped into seven different types:- (i) disc space narrowing only (ii) kissing lesions; (iii) wedge collapse of vertebra; (iv) vertebra plana; (v) lesions localised in the vertebral body and/or its appendages; (vi) para-spinal abscesses; (vii) complete destruction of vertebral body. The dorsolumbar region was the most frequently involved with D.11 vertebra being most often affected. The maximum number of vertebrae involved was eight but involvement of two was the most frequent. Some uncommonly reported radiological features encountered include bone sclerosis, intervertebral non-osteophytic bony bridge formation and skip lesions.
Three cases of multiloculated lesion of the jaw (two in the mandible and one in the maxillar) closely mimicking ameloblastoma are described. Histology showed all three to be fibrous dysplasia. Against a diagnosis of ameloblastoma were (1) the relative fuzziness of the margins of the loculi and septae; (2) the mineralization of the matrix which gave a ground-glass background instead of the distinct radiolucency seen in ameloblastoma; and (3) the non-resorption of the dental root apices within the lesion.
A Nigerian male with typical features of Albright's syndrome will be described. Although the lesions were predominantly unilateral, his main complaint was that of severe facial deformity. He had a radical excision of the facial lesion which was followed by a rapid recurrence. The differential diagnosis of Albright's syndrome will be discussed.
Two cases of Paget's disease presenting with deafness are described. Tomography of the petrous bones showed, in both cases, an upward tilt of the long axes of the bones including their auditory canals, generalized sclerosis of the petrous pyramids and enlargement of the ossicles. In one case, there was narrowing of the internal auditory canal. Review of the literature revealed three radiological phases in Paget's disease of the temporal bone:--(i) early changes consisting mainly of demineralisation; (ii) an intermediate phase consisting of diminishing visibility of the semicircular canals and cochlea; and (iii) a late phase consisting of complete blotting out of the structures of the optic capsule and replacement of the ossicles by Pagetic bone. Our two cases fall within the last phase.
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The clinicoradiologic features and surgical treatment of fibrous dysplasia of the jaws in forty-seven Nigerian patients are described. Marked facial deformity and functional disturbances were the main indications for operation. We noticed one case of malignant transformation. It is our opinion that a more-than-usual aggressive excision is indicated in Nigerian patients.
Intravenous urographies carried out routinely on 216 cases of vesico-vaginal fistulae were reviewed. All the patients had suffered from urinary incontinence following obstructed labour for periods varying from immediate post-partum period to as long as 35 years with the majority (48%) presenting in the first year of the disease. One hundred and eleven patients (51-4%) showed no urinary tract abnormality. Calyceal abnormality was graded from 1-5 in ascending order of severity. The most frequent abnormality was Grade 1 (or minimal calyceal blunting) found in 75 (71%) of 105 cases showing lesions. Ten patients had non-functioning kidneys. There was no correlation of severity of calyceal grading with duration of the disease. Other notable changes were hydroureter in 75 (34%), medial deviation of the terminal ureters in 21 (9-7%) and bladder calculi in four. The study reveals a high risk of morbidity to the kidneys in patients with vesico-vaginal fistulae and the predominant role of fibrous itssue in tis genesis is postulated.
We present 30 cases of ankylosis of the lower jaw following cancrum oris. The clinical and radiological findings, the anesthetic methods, and the surgical management are described. Adequate excision of limiting scar and any bony ankylosis, with immediate mucosal or skin coverage of any raw surfaces created, is the proper approach. Postoperative jaw exercises and the use of a bite block may be helpful.
The clinical and angiographic findings in 5 consecutive patients with congestive cardiac failure are presented to illustrate the pitfalls in the clinical diagnosis of endomyocardial fibrosis. In one patient the clinical diagnosis was confirmed at angiography while another patient who had angiographic evidence of early right ventricular endomyocardial fibrosis was diagnosed clinically as mitral stenosis. In 2 patients the clinical diagnosis was erroneous, there being no evidence of endomyocardial fibrosis on angiography. The fifth patient, who had angiographic evidence of idiopathic cardiomegaly, was diagnosed clinically as either idiopathic cardiomegaly or advanced left ventricular endomyocardial fibrosis. In tropical countries, where endomyocardial fibrosis, rheumatic heart disease, and idiopathic cardiomegaly are common, accurate clinical diagnosis of endomyocardial fibrosis is often difficult and angiographic studies are essential for confirmation.