[Physical activity and health].
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Biomedical subjects
Publications and source records attributed to S B Strømme.
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Excretion of uromucoid, albumin and casts in urine were determined in twenty well-trained men, ten aged 20-30 years, and ten aged 50-60 years, before, during and after a 70 km cross country ski race. During the race there was only a slight increase in uromucoid excretion, but a marked increase in the excretion of casts and albumin. The older subjects had a tendency to lower urine output during the race compared to the younger group. Reduction of urine output below ca. 25 ml/h was accompanied by a conspicuous increase in urine cast and albumin concentrations, with only a slight increase in uromucoid concentration, and even a reduction in uromucoid excretion. No significant relationship was found between cast excretion and uromucoid concentration. Thus the gross cylindruria observed during longstanding exercise must be ascribed to other urinary factors facilitating the formation of casts.
Serum high density lipoprotein (HDL) cholesterol, total serum cholesterol and triglycerides were determined in twenty men before, immediately after, and 1, 2 and 4 days after a 70 km cross-country ski race. HDL cholesterol increased by 12% of the pre-race level immediately after the race, rose further to 17% above the initial level on the following day, and was still elevated 4 days after the race. LDL + VLDL cholesterol, however, showed a tendency to decrease immediately after the race and was reduced by 17% and 11% of the pre-race level on the following 2 days. Triglycerides were reduced by 30% of the initial level immediately after the race, were still low on the following day, but were restored to normal 2 days after the race. It is concluded that a single exposure to prolonged heavy exercise induces changes in the HDL metabolism, showing that the physical exercise per se plays an important role for the increased HDL level seen in well-trained athletes.
Six endurance-trained young men were subjected to a 4 min maximal aerobic treadmill run (100% of VO2 max), after active or passive warm-up or rest on separate days. The increase in body temperature during the active and passive warm-up was controlled, so that the temperature reached the same level, before the subject was exposed to the maximal exercise. On average the rectal temperature rose to 38.3 degrees C (range 38.1-38.6 degrees C). The standard work resulted in a significant higher oxygen uptake, lower lactate concentration and higher blood pH when the work was preceded by active warm-up as compared with passive or no warm-up. The difference in total oxygen uptake during the run between the active and passive warm-up procedure was 0.8 1. No significant difference in minute volume of expired air or respiratory quotient was found. It is concluded that the physiological effects of a thorough active warm-up may be of substantial benefit to athletic performance.
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Resting pulmonary plasma and blood volumes (PPV and PBV), interventricular circulation time (IVCT), cardiac and stroke index (CI and SI), heart rate (HR), total plasma and blood volumes (PV and BV) were determined in athletes (two male groups representing different types of sport activities, and one female group) and compared with those of non-athletes (one male and one female group). In addition to high maximal aerobic power, the athletes were characterized by greater SI, BV and PV and lower resting HR than non-athletes, PPV and PBV were significantly larger and IVCT significantly longer in the trained than in the untrained groups, probably reflecting an improved capacity of the pulmonary circulation. PPV as per cent of PV was almost equal in all the groups, indicating the same distribution of plasma between the pulmonary and systemic circulation. The data also indicate that total blood volume is an important determinant of the magnitude of the pulmonary vascular bed. The increased volume of flowing blood and increased stroke volume in athletes probably allows for a reduction in flow velocity and thereby a reduction in kinetic energy.
Venous plasma and urine amino acids and urea were measured in ten well-trained men, aged 23--45 years, in connection with a 70 km cross-country ski race, lasting 4.39--6.04 h, leading to slight dehydration. The estimated urea production rate during the race was of the order 7.6 mumol/min, kg b.wt, i.e. twice the rate for such men on ordinary protein intake, during ordinary activity, thus suggesting increased protein catabolism. The race led to a fall of the total plasma amino acid concentration to about 60% of the pre-race level. In particular, the branched chain amino acids (valine, iso-leucine, leucine) and alanine were markedly reduced, whereas the S-containing amino acids (taurine, cystine, methionine) and the aromatic (phenylalanine, tyrosine, trytophan, histidine) and glutamine/glutamate were increased, unchanged or only moderately reduced. It is concluded that prolonged heavy exercise is accompanied by increased protein catabolism and changes in the plasma amino acid concentrations similar to those observed during prolonged starvation, but differing from those seen at heavy exercise of less than 2 h duration or prolonged exercise of moderate intensity.
Serum and urine osmolality and creatinine were measured in fifty-eight well-trained men, aged 21-57 years, in connection with three 70 km cross-country ski races taking place under essentially the same external circumstances, leading to slight dehydration. Although the race urine flow was low, 0.51 (0.05-1.10) ml/min, the urine osmolality and the urine to serum osmolality ratio were relatively low, averaging 860 (399-1220) mosm/kg H2O and 2.84 (1.32-4.10), respectively. Decreasing urine flow and endogenou- creatinine clearance were associated with decreasing urine to serum osmolality ratio, indicating declining urine concentrating ability. Thus, the data confirm the author's recent suggestion, based on the measurement of a limited number of urine solutes, that during prolonged heavy exercise a decrease in urine flow and glomerular filtration rate is accompanied by a decline in the urine concentrating ability.
It has previously been suggested that diving bradycardia might be more pronounced in physically trained subjects than in unconditioned ones. Therefore, the cardiac responses to apneic face immersion in water of 25 +/- 1 degree C during rest and exercise in 24 males and females, ranging in age from 21-37 years, were compared to the subjects' levels of physical fitness, as estimated by maximal aerobic power. These values ranged from 46-74 ml.kg-1.min-1. The diving bradycardia was greatly intensified when the face immersion was superimposed on a state of apneic exercise. However, a correlation of the individuals' maximal aerobic power and the mean degree of bradycardia displayed during various maneuvers of apneic face immersion did not approach statistical significance. It is concluded that there exists no relationship between bradycardia and physical fitness, as judged from maximal aerobic power.