Tetrahydrobiopterin metabolism in depression.
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Adult↗
Biomedical subjects
S B Whitburn
Publications and source records attributed to S B Whitburn.
Tetrahydrobiopterin metabolism in the temporal lobe of patients dying with senile dementia of Alzheimer type.
There is a defect in tetrahydrobiopterin metabolism in brains from subjects with senile dementia of Alzheimer type compared to age-matched controls. This defect results in lowered total biopterin concentrations in brain. Brains from subjects with senile dementia of Alzheimer type retain their ability to synthesis neopterin and have normal dihydropteridine reductase activity, indicating a specific loss of ability to convert dihydroneopterin triphosphate to tetrahydrobiopterin.
Aged↗
Tetrahydrobiopterin metabolism in senile dementia of Alzheimer type.
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Aged↗
Synchrotron x-ray diffraction study of corneal stroma.
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Animals↗
Interpretation of the meridional x-ray diffraction pattern from collagen fibrils in corneal stroma.
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Animals↗
The distribution of electron density in corneal collagen fibrils.
Using high intensity synchrotron X-ray diffraction data, an electron density profile has been obtained for the collagen fibrils in corneal stroma at higher resolution than has been possible before. The details within this electron density distribution are discussed in terms of the collagen and its interactions with other components present in the tissue.
Collagen↗