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Biomedical subjects

S Bános

Publications and source records attributed to S Bános.

7 recordsLinked to original sources

Bone changes in young mice with impaired lymphoid system.

Disturbances of osseal growth were observed in young mice with their lymphoid system affected by antihymocyte serum or mitolactol (dibromodulcitol) treatment. These bone changes were similar to those observed in germ-free and neonatally thymectomized mice as well as in mice suffering from a graft vs. host reaction. Their severity was in direct correlation with the disturbance of the thymus dependent lymphoid system. Not only immunological adaptation but also normal bone growth appears to require an intact thymus and thymus dependent lymphoid system.

Animals↗

Course of lymphocytic choriomeningitis virus infection in young and aged mice.

The course and histological picture of intracerebral LCM virus infection was found to differ in mice with their thymus displaying an age-dependent involution and in young adult animals. Signs of lymphocytic choriomeningitis were absent in 75 per cent of the aged animals. The change of the characteristic clinical and histological picture referred to the decreased cellular immune response of aged animals, ascribed to the age-dependent involution of the thymus.

Age Factors↗

Combined phytohaemagglutinin and dianhydrodulcitol treatment of lymphocytic choriomeningitis virus infection in mice.

The course of intracerebral lymphocytic choriomeningitis (LCM) virus infection was studied in mice treated simultaneously with dianhydrodulcitol (DAD) and phytohaemagglutinin (PHA). Earlier experiments revealed that DAD decreased and PHA enhanced the cellular immune response of mice to LCM virus infection. On applying the treatments simultaneously they inhibited each other and neither the decreasing effect of DAD nor the enhancing effect of PHA on the cellular immune response could be observed.

Animals↗