PubMed Health⌕ Search

Biomedical subjects

S Baba

Publications and source records attributed to S Baba.

At least 1,189 records · Page 66Linked to original sources
PubMed1976

Transplantation of human renal cell carcinoma to the nude mice: as an intermediate of in vivo and in vitro studies.

Five human renal cell carcinomas were transplanted successfully to nude mice fed and grown under a specific pathogen-free condition. The histology of the transplanted tumor tissue was a close reproduction of the original human cancer tissue in situ. The transplanted tumor tissue possessed an abundant supply of blood vessels, which was considered to be of host animal origin. All transplanted tumor cells grew easily when transferred to an in vitro cell culture system from the nude mice. In this latter cell culture system tumor cells demonstrated a growth pattern characteristic of epithelial cells. The electron microscopy of these cells showed some characteristic morphological features that indicated their cytological origin.

Adenocarcinoma↗
PubMed1976

Isolated corticotrophin-deficiency found through alcohol-induced hypoglycemic coma.

A case of hypoglycemic coma after alcohol ingestion was observed in a chronic alcoholic. Upon close examination isolated corticotrophin-deficiency was found. It is suggested that ethanol-induced hypoglycemia may be consistent with dysfunction of mitochondria in hepatic cells and that there may be disorder of the hypothalamus in the chronic drinker.

Adrenocorticotropic Hormone↗
PubMed1976

Electrophoretic pattern of amylase isoenzymes in serum and urine of normal persons.

We separated and measured amylase isoenzymes in the serum and urine of 3036 normal persons by electrophoresis on a thin layer of polyacrylamide gel. We wished to establish the normal pattern of these isoenzymes and to evaluate the usefulness of this method of electrophoresis in clinical diagnosis. Results for patients with hyper- or hypofunctioning pancreas and salivary glands suggested that essentially all the isoamylases in human serum and urine are derived from the salivary glands and the pancreas, and revealed that isoamylases of more than 98% of normal persons consisted of two major isoenzymes and two to three minor ones. Although these observations indicate that data on changes in the proportion of amylase activity of each isoenzyme can be useful in clinical medicine, the following points should be remembered: (a) quantitative differences in the isoenzyme pattern were observed, depending upon the condition of the samples; (b) because the proportion of isoamylase activity in serum of different normal persons differs, seriatim determination of amylase isoenzymes is necessary; and (c) because five different genetically controlled types of isoamylases were observed in normal persons, genetic investigations are also necessary.

Adult↗
PubMed1976

Enflurane anaesthesia for removal of aldosterone producing adenoma.

In a 31-year old woman with a six year history of headache and hypertension a diagnosis of primary aldosteronism was made on the basis of urine samples containing 45 mug/day of aldosterone. The preoperative systemic blood pressure was 240 mm Hg systolic and 120 mm Hg diastolic. The serum potassium level was 2.6 mEq/L and other laboratory findings were within normal limits. The patient was to undergo operation. Pre-medication consisted of oral pentobarbitone, intramuscular pethidine and atropine. For induction of anaesthesia, enflurane 2.0-2.5% maximum was given with O2 (21/min) and N2O (61/min); no intravenous agents were used. Suxamethonium chloride 40 mg was administered to facilitate endotracheal intubation. Anaesthesia was maintained with enflurane 1.5-2.0% with 50% N2O and O2. Tubocurarine 27 mg was given for muscle relaxation. When the tumour was manipulated, systemic arterial blood pressure was elevated again to 190 mm Hg systolic and 120 mm Hg diastolic. After removal of the tumour, the arterial pressure and heart rate were stable and recovery from anaesthesia was without circulatory or respiratory complications. Plasma aldosterone levels reached a maximum when the tumour was manipulated and fell to normal levels on the second post-operative day. Cortisol levels were not altered markedly even when the tumour was handled. These data imply that adrenocortical response to enflurane anaesthesia as jadged by plasma aldosterone levels would be different from that as estimated by plasma cortisol levels.

Adenoma↗
PubMed1976

Selective intraarterial steroid injection in ulcerative colitis.

Angiography was performed in 11 patients with ulcerative colitis and prednisolone injected directly into the superior and inferior mesenteric arteries in 10 patients. Hypervascularity of the affected regions was a common finding, but early venous filling was noted in only 5 cases out of 11. Good results were obtained by intra-arterial steroid injections.

Adolescent↗