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Biomedical subjects

S Barcikowski

Publications and source records attributed to S Barcikowski.

At least 19 recordsLinked to original sources
PubMed1999

Right ventricular morphology and function after pulmonary resection.

OBJECTIVE: To identify the effect of pulmonary resection on right ventricular performance and its possible contribution to mortality and morbidity. METHODS: Before and 2 days after pulmonary resection for primary lung cancer in 31 patients (21 males; ages 32-69 years), echocardiographic examinations of the right ventricle were performed. Systolic, diastolic and stroke volumes as well as right ventricular ejection fraction were estimated. Right ventricular volumes were calculated using the subtracting method. RESULTS: Right ventricular end-diastolic volume index increased significantly in patients after pneumonectomy: 80.4+/-7.2 ml/m2 versus preoperative evaluation: 66.1+/-5.2 ml/m2 (P = 0.031). In patients who underwent pneumonectomy right ventricular ejection fraction significantly decreased from 48+/-5.0% preoperatively to 39%+/-4.1% after surgery (P = 0.027). Fourteen patients after pneumonectomy had development of supraventricular arrhythmias postoperatively. These patients had much higher right ventricular end-diastolic volume index (76.3+/-6.4/82.1+/-7.4; P = 0.032) and lower right ventricular ejection fraction (42+/-4.3/37+/-3.9; P = 0.021) after surgery in comparison with patients who had normal sinus rhythm postoperatively. CONCLUSION: Pulmonary resection caused a significant dilatation and dysfunction of right ventricle in the early postoperative period. Early detection of deterioration in right ventricular function after pneumonectomy may provide the opportunity for interventional therapy.

Diastole↗
PubMed1998

Cardiorespiratory function before and after operation for pectus excavatum: medium-term results.

OBJECTIVE: The study was undertaken in order to assess the degree of impairment of the cardiovascular system in patients with funnel chest and to investigate any changes caused by surgical correction. METHODS: Echocardiographic examinations with systolic, diastolic and ejection volume indices calculation as well as pulmonary function tests were performed before surgery and at medium-term follow-up on 34 patients who were operated on for pectus excavatum between 1987 and 1992. RESULTS: The mean age was 13.4 years. There were 70.6% males. Pulmonary function was found to be restricted preoperatively in 18 patients. Inspiratory vital capacity and forced expiratory volume were increased or did not change at follow-up (5 years) in these patients. In cases with normal or moderately restricted pulmonary function (inspiratory vital capacity, forced expiratory volume more than 75% predicted) the reduction of lung function was noted after surgery. Marked haemodynamic improvement was found with the increase of diastolic and ejection volume of both heart ventricles (mainly right one). The improvement was more evident in patients with severe deformations. CONCLUSION: Only in case of severe reduction of lung function in a patient with funnel chest can one expect improvement after surgery. Sternocostal elevation improves function of both heart ventricles at rest.

Adolescent↗
PubMed1995

Video-assisted thoracoscopy for closure of a bronchial stump fistula.

It is thought that thoracoscopic closure of a bronchial stump fistula is beyond the capabilities of current thoracoscopic techniques. We describe the successful use of thoracoscopy in the therapy of a late right main bronchial stump dehiscence after pneumonectomy and chemotherapy of a stage IIIA adenocarcinoma. We clipped the fistula with a Multifire Endo Hernia Stapler (Auto Suture) and we obtained intraoperative airtight closure of the fistula.

Bronchial Fistula↗
PubMed1993

[Effect of correcting funnel chest on respiratory function].

The authors discuss the results of pulmonary function tests performed at rest in 25 patients treated for pectus excavatum. Surgical correction of the lesion was performed by resection of the deformed costal cartilages, longitudinal and transversal sternotomy, stabilization of the anterior chest wall with Kirschner wires. Control tests carried out 6 months following the surgical correction. In cases of severe deformation of the chest wall a decrease of pulmonary function indices was evident. Following the surgical correction all spirometric indices increased.

Adolescent↗
PubMed1991

[Heart injury caused by air shock wave trauma].

The aim of the study was the estimation of heart muscle in response to air shock wave trauma. The animals were divided into four groups according to the time between trauma and the examination (3, 24, 48 and 120 hours). In all groups of animals ecg was performed and plasma level of creatinine kinase (CK), cardiac isoenzymes (CK-MB), lactic dehydrogenase (LDH) and its isoenzymes (LDH1-2) and alpha hydroxybutyrate dehydrogenase (HBDH) were determined. CK-MB activity as a percent of CK activity and rate of LDH isoenzymes activity were calculated. Morphologic estimation of heart injury based on macroscopic observation, histology and coronarography of heart specimens was performed. It was revealed that pathologic changes in ecg indicating intracardial conduction disturbances occur most intensively in first ten minutes after trauma. Plasma CPK, LDH and LDH1-2 activity increased significantly after 120 hrs following trauma. Morphologic manifestation of heart damage was multifocal injury of heart muscle.

Animals↗
PubMed1989

[Modified Ravitch operation in the treatment of patients with funnel chest].

The characteristic traits of funnel chest have been presented and the clinical results of surgical treatment in 13 patients by the modified Ravitch method have been discussed. Nine results were excellent and four results were good. A marked improvement of general physical function of the patients due to the increase of respiratory system efficiency and a good cosmetic effect were found. The modification of the operation consists in additional longitudinal osteotomy of the sternum, suturing of the manubrium to the sternum shaft, non-suturing of the rib cartilages after resection, filling of the through-like groove in the reposited sternum with the fragments of the resected rib cartilages, and immobilization of the fragments of the longitudinally osteotomized sternum that are inserted crosswise with several (usually three) Kirschner wires, based on the thorax.

Adolescent↗
PubMed1988

[Lung injuries caused by explosion in rabbits. 3. The behavior of the lung after injury].

The behaviour of the pulmonary activity was investigated in 30 rabbits after a blast. The estimation was carried out by the results of volumetric, gasometric, and radio-isotopic researches. The results show a considerable disturbance of the pulmonary activity which leads to respiratory insufficiency in rabbits after a blast of medium strength. The restriction type was dominant in the disturbance of the ventilation. An impairment of the gas diffusion is the consequence and leads to hypoxia and to a compensated respiratory acidosis.

Animals↗
PubMed1988

[Lung injuries caused by explosion in rabbits. 1. The experimental model of the injury].

A model for producing blasts of medium strength was developed. The injuries lead to the death of 25 to 50% of the experimental rabbits. The injuries were tested physically by direct measurements. The explosion of 225 g TNT in the air in 110 cm distance killed 35% of the rabbits. The corpus of the rabbit absorbed 67% of the energy of the blast in 0.46 ms in average. The average of the maximum positive pressure in the blast was 25.4 +/- 3.1 bar.

Animals↗
PubMed1988

[Lung injuries caused by explosion in rabbits. 2. Pathogenetic mechanisms in lung injury (a hypothesis)].

A hypothesis of the pathogenetic mechanism of the pulmonary changes after the injury is introduced. Basis are the results of the morphologic estimation of the lung traumas by blast with known energy in rabbits. The reason is the lung deformation by the sudden pressure increasing in the thoracic cavity and the volume reduction of the thorax. The deformed lungs were pressed against the thorax wall in the region of the smallest deformation.

Animals↗
PubMed1980

[Ultrastructural changes of the lungs in experimental burn shock].

The alteration of the ultrastructure of lungs was investigated in the course of the early shock period in the experimental burn disease. The histologic investigations of the lungs were carried out with the Philips 300 electron microscope. A stronger scaling of the surfactant of alveoli was observed in the first days after the burn. Number and size of the myelin structures in the pneumocytes typ II increased simultaneously. The walls of the capillaries were not injured. An edema of th capillary endothelium was observed frequently. The most extensive alterations of ultra structure of lungs appeared in the course of the burn disease on the first or the second day after the thermic injure.

Animals↗
PubMed1979

[Experimental gluing of the pleural cavity].

In experimental research on rabbits the authors assessed the usefulness of tissue adhesive-GRF in obtaining tissue union in the pleural cavity to replace aspiration drainage after thoracosurgical operations. The experiments were carried out on rabbits under general anaesthesia in two groups. First group had thoracotomy and after expansion of the lungs the chest was closed tightly. In second group after thoracotomy the lungs were stabilized with gelatin-resorcin-formaldehyde glue. Aspiration drainage was not used. The observation included: radiologic examination, measurements of pulmonary ventilation using Wright's volumometer and gasometric determination. Moreover the alveolar-capillary oxygen difference and the percent of lung shunt were determined. The authors underline good function glued lungs.

Animals↗