Biomedical subjects

S Barg

Publications and source records attributed to S Barg.

28 records · Page 2Linked to original sources

PubMed1987

Sarcomas of the jaw.

A retrospective analysis is made of 61 patients with clinical and histological diagnosis of pure sarcomas of the jaw treated between 1950 and 1984. Surgery was the treatment of choice in 41 cases. Biopsy or palliative treatment were undertaken in the remaining patients. Twenty-four cases relapsed before 12 months, and 12 relapsed before 3 years. Twenty-four died before 12 months, nine before 2 years, and three after 2 years. At present there is no evidence of disease in eight patients: three out of 25 fibrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), three out of 15 chondrosarcomas (one more than 1 year, one more than 13 years, and one more than 14 years), and two out of 15 osteosarcomas (one more than 18 years). The prognosis is gloomy. However, an early diagnosis and radical surgery contribute to an improvement in the course of the disease.

Adolescent↗

PubMed1985

Combined polychemotherapy in the treatment of primitive lung cancer of the "non-oat cell" type.

Forty-one patients (30 males, 11 females; mean age 49.7 years) with diagnosis of the "non-oat cell" type of lung cancer were studied. All patients were included in a randomized treatment design (regimens A and B) and completed six full cycles of polychemotherapy. Only 28 of the 41 patients proved evaluable. The performance status was 0-2 in 20 subjects (71.4%) and 3-4 in 8 (28.6%). The total number of patients achieving partial and complete responses was 20 (71.4%), of whom 14 (70%) received CDDP and the other 6 DDR. A progression of the disease was seen in 8 patients (28.6%), of whom 5 (62.5%) received DDR and the other 3 (37.5%) CDDP. An increase in body weight (3-8 kg) was observed in 15 patients (53.6%). Twenty-four of the 28 patients (85.7%) had a subjective feeling of well-being throughout the 6 cycles of chemotherapy. Nausea and vomiting and alopecia were the most frequent side-effects. The most important complications were paralytic ileus in 2 cases and a darkish manifestation in forearm and hand tissue due to vinblastine extravasation in another 2 cases. Haematological toxicity was found to be acceptable: leucopenia (less than 3.000) in 30 patients (73.2%); and thrombocytopenia (less than 100.000) in 12 patients (29.2%), which proved reversible. Some modalities relative to treatment schemes and the incorporation of additional agents are discussed.

Adult↗

PubMed1983