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Biomedical subjects

S Barsky

Publications and source records attributed to S Barsky.

At least 19 recordsLinked to original sources
PubMed1992

Monosymptomatic hypochondriacal psychosis: belief of contracting rabies.

The authors describe a forty-one-year-old female with possible monosymptomatic hypochondriacal psychosis (MHP): a delusional belief that she had contracted rabies. This is the first report of this type of delusion in MHP. The patient failed to respond to multiple somatic therapies and finally made a serious suicide attempt. The authors discuss the reasons for the failed treatment and suggest a sequential protocol for treatment of MHP based on the current literature.

Adult↗
PubMed1989

"Koro" (genital retraction syndrome): psychotherapeutic interventions.

"Koro" is a belief or delusion of retraction of the penis into the abdomen. Originally thought to be a Chinese and Indonesian culture-bound syndrome, it has recently been noted to occur in "Western" patients. Two Western patients with this syndrome are described and their psychotherapeutic treatment and outcome outlined. A stepwise approach to the treatment of the Koro symptom is suggested.

Adult↗
PubMed1987

Scleromyxedema with corneal deposits.

Scleromyxedema (Arndt-Gottron syndrome) is a rare cutaneous disease in which hyaluronic acid is deposited in the dermis. The authors describe a patient with scleromyxedema and corneal deposits. A corneal biopsy demonstrated hyaluronic acid deposition in the corneal stroma and amyloid P component in Bowman's membrane. This is the first report of scleromyxedema involving the cornea. It is also the first report of amyloid P component deposition in the cornea occurring independent of corneal amyloid deposits.

Adult↗
PubMed1985

Chemoattractants in fibrotic disorders.

Fibrosis represents an excessive deposition of connective tissue which impedes the normal functions of an organ or tissue. The mechanisms leading to this increased deposition of connective tissue may be similar to those occurring in normal wound repair. We have previously shown that the repair process involves the migration of connective tissue cells to the site of injury and their subsequent proliferation. One of the principal factors controlling these events appears to be the platelet-derived growth factor (PDGF). PDGF acts as a potent chemoattractant and mitogen for connective tissue cells but not other cell types. In addition to PDGF, factors produced by monocytes and tissue macrophages also act as chemoattractants for connective tissue cells. These observations suggest that such activities may be abundant in areas of inflammation. In normal repair these factors would be present for a relatively short period of time, whereas in fibrosis the chronic inflammatory response could maintain a constant or repeated release of such factors. This would recruit additional connective tissue cells to the area of inflammation, changing the cellular composition of the affected organ or tissue, resulting in an expansive and permanent nodule of connective tissue.

Animals↗
PubMed1985

Benign cephalic histiocytosis. A case report and ultrastructural study.

A 4-year-old Hispanic boy had an asymptomatic eruption of red-brown macules and papules on the face, neck, trunk, and upper extremities. Examination of the skin lesions by light microscopy revealed a diffuse infiltrate of histiocytes in the upper dermis. Examination by electron microscopy showed wormlike inclusion bodies within the histiocytes. A diagnosis of benign cephalic histiocytosis was made on the basis of these distinct clinical, histologic, and ultrastructural features.

Biopsy↗
PubMed1985

Zosteriform connective-tissue nevus.

Zosteriform connective-tissue nevus, because of its distribution and histopathologic characteristics, is considered to be a separate entity. The only previous case of zosteriform connective-tissue nevus to be reported in the American literature was in 1944. We report and discuss a similar case.

Adult↗
PubMed1984

Pigmented basal cell epithelioma arising in the scar of an onchocerciasis nodule.

Pigmented basal cell epithelioma (BCE) arose in the scar of an onchocercoma nodule in a 45-year-old white man. There were extensive fibrosis, inflammation, epidermal hyperplasia, and nests of basal cancer cells. The authors believe that the development of epithelioma in this case was more than a chance occurrence. There is little doubt that the malignant change was subsequent to the scarring-proliferative process of the disease. To the authors' knowledge, this complication has not been reported previously.

Basal Cell Carcinoma↗
PubMed1984

A controlled study of suicide pacts.

The records of the Dade County Medical Examiner's Office were reviewed and 20 suicide pacts (double suicides) were identified. These 40 suicide pact victims were compared using a standardized instrument to 120 randomly selected single Dade County suicides, from the same time period and area. Suicide pacts were also compared based on their composition (spouses, other intrafamilial pairs, and lovers). Suicide pact victims differed significantly from single suicides on several variables, including the tendency to use guns, leave suicide notes, have alcohol-positive blood, be older, be less depressed, and to suicide in the morning hours.

Age Factors↗
PubMed1984

Benign cephalic histiocytosis.

A 2-year-old boy was seen because of an extensive asymptomatic papular eruption on the face, neck, and shoulders of 18-months' duration. A skin biopsy specimen revealed cellular infiltrates composed predominantly of histiocytes. Electron microscopy of biopsy material disclosed "comma-shaped" inclusion bodies in the cell cytoplasm, consistent with the findings described in benign cephalic histiocytosis. To the best of our knowledge, this is the first report of this clinical entity in the American literature.

Child, Preschool↗
PubMed1983

An epidemic of infection with Trichophyton tonsurans revealed in a 20-year survey of fungal infections in Chicago.

Trichophyton tonsurans has long been recognized as an important, but hitherto uncommon, cause of tinea capitis in the United States. Today it is known to be more common, but infection of the glabrous skin by this organism is still not well appreciated. In an epidemiologic study during the two decades from 1961 to 1980, 1,292 isolates of thirteen species of dermatophytes were obtained from patients at Cook County Hospital, Chicago. During the last 3 years of study, T. tonsurans accounted for 207 cases (96%) of tinea capitis and ninety-seven cases (75%) of tinea corporis. Ninety-five percent of cases of tinea capitis caused by T. tonsurans occurred in children (59% girls, 41% boys). By contrast, 62% of cases of tinea corporis caused by that organism occurred in adults. Substantially more women than men were affected in a ratio of nearly six to one. The majority of the women were between 15 and 29 years of age; about half of all had lesions on the arm. Over the past 20 years, T. tonsurans has emerged as a major cause of both tinea capitis and tinea corporis in Chicago. The disproportionate number of cases of tinea corporis in women of childbearing age may be due to their more frequent contact with infected children.

Adolescent↗
PubMed1983

Acrodermatitis enteropathica.

A case of acrodermatitis enteropathica belatedly recognized in a pregnant 23-year-old woman is reported. The condition was not specifically diagnosed during childhood. It cleared at puberty but recurred during two of three pregnancies in the form of pustular, vesiculobullous, and psoriasiform lesions. There were no associated signs or symptoms in other organs. Initial diagnoses upon the recurrence during the third pregnancy were herpes gestationis and impetigo herpetiformis. A markedly decreased serum zinc level (18 micrograms/dl) was found. Treatment with zinc sulfate was instituted, and within 3 days the cutaneous lesions began to clear. Two months after the birth of a healthy child, and without further therapy, all lesions had resolved and the serum zinc level was nearly normal. Acrodermatitis enteropathica should be considered in the differential diagnosis of unresponsive bullous dermatoses occurring during pregnancy.

Acrodermatitis↗
PubMed1983

Lupus vulgaris.

Explore the source record for details and available documents.

Female↗
PubMed1982

Warty dyskeratoma.

A 43-year-old man with a crusted papule on the cheek was found to have a squamous cell carcinoma of the lung. Histologic examination of the skin lesion showed the characteristic features of warty dyskeratoma. A rare clinical photograph is presented and the clinical and histopathologic features are reviewed.

Adult↗