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Biomedical subjects

S Behmard

Publications and source records attributed to S Behmard.

9 recordsLinked to original sources
PubMed1983

Epidemiologic study of oral cancer in Fars Province, Iran.

From January 1962 to December 1978, 381 consecutive cases of oral cancer in Fars Province were analyzed and studied. The incidence of oral cancer was found to be 1.13/100 000. The male/female ratio was 5:1, the median age of oral cancer was 55 years. 97% of the oral cancer was squamous cell carcinoma. The most commonly affected oral site was the lower lip, next was the tongue. Tobacco smoking and opium addiction were more common among the affected compared with the control group. Dental sepsis and poor oral hygiene were common in both groups. Malnutrition, anemia and liver dysfunction were common in the examined sample and are thought to be possible causative factors especially in those with no smoking habits. The role of general dental practitioners was limited, they suspected and referred only 13 advanced cases.

Adolescent↗
PubMed1979

Opium: a potential urinary bladder carcinogen in man.

Evidence is presented that opium addition is a risk factor for cancer of the bladder. A case-control study of 99 bladder cancer patients admitted to Nemazee Hospital in Shiraz, Iran was evaluated. Cancer patients and controls, matched by age and sex, were analyzed as to their opium and/or cigarette smoking habits. A high correlation between opium addiction and bladder cancer has been observed. This evidence significantly exceeded the one observed in relation to cigarette smoking only. The sex ratio for this cancer site, from hospitalized cases in Southern Iran, is estimated to be about nine male cases per one female case. This high male to female ratio was attributed to the greater addiction of males to opium. It was concluded that opium and, more likely, its pyrolysis derived fractions may represent potential bladder carcinogens in man.

Adult↗
PubMed1979

Discrepancies in the histological diagnosis of hydatidiform mole.

Sections of tissue from 256 patients on which a histological diagnosis of hydatidiform mole had been made were reviewed by a visiting pathologist. There was agreement between the reporting pathologists and the visiting pathologist in only 55.1 per cent of cases, a less severe diagnosis was made by the visiting pathologist in 42.2 per cent of cases. The disagreement was as high as 66.6 per cent with pathologists who rarely worked in the gynaecological field. This study casts serious doubt on the consistency of the histological diagnosis of hydatidiform mole made in any one laboratory and between different laboratories. It is suggested that in epidemiological studies the diagnosis should be made by a panel of pathologists using strict histological criteria and in an individual laboratory diagnosis should be made or confirmed by a pathologist experienced in gynaecological pathology.

Diagnostic Errors↗
PubMed1978

Cancer of the bladder in Southern Iran.

The sex ratio for cancer of the bladder from hospitalized cases in Southern Iran is estimated to be about nine male per female cases. Differential case ascertainment may account for some of the discrepancy; however, no other major cancer site has a sex ratio of this nature, utilizing the same data. Since industrial carcinogens and other predisposing factors, such as schistosomiasis, are rare, the role of other possible etiologic factors, such as opium addiction, which is predominantly male, were considered and discussed.

Adolescent↗
PubMed1977

Cancer of the esophagus in southern Iran.

The minimal yearly incidence of cancer of the esophagus in Fars Province in Southern Iran, based on hospital records in the capital city, is five to 10 times as high as the yearly incidence in Connecticut for the age group 15-44. Since these represent only a portion of cases among residents of the Province, the true rate is probably considerably higher. An unusual proportion of these cases (32% overall) presented with primary tumor in the upper third of the esophagus. The location of the tumor was related strongly to age, but not to sex after taking age into account. The proportion of esophageal cancer cases who were female was significantly greater than that of other GI tract cancers combined. It appears that the risk in males and females in this area is at least nearly equal, and risk could conceivably be higher in females (similar to the appearance of the disease in Northern Iran).

Adenocarcinoma↗
PubMedDate not supplied

Cytologic screening for cervical cancer in southern Iran.

In an 11 year study of cytologic examinations from the southern part of Iran with a 99 percent Moslem population, the prevalence rate of invasive cervical carcinomas in 35,222 women screened for the first time was 2.3 per 1,000 examinations. With the initiation of a mass screening program begun in 1974, the rates of CIS and moderate and severe dysplasia rose threefold. These findings indicate that carcinoma of the cervix is an important problem in Iran, despite previous reports of the contrary. There is, thus, a clear need for encouraging and expanding the mass screening program which has been initiated in this country.

Adolescent↗
PubMedDate not supplied

Diagnostic accuracy of endoscopy with brushing cytology and biopsy in upper gastrointestinal lesions.

Because of the high rate of diagnostic error with routine barium X-ray studies in detection of upper gastroesophageal lesions, a prospective investigation was undertaken to evaluate endoscopy together with brushing cytology and biopsy. Ninety-nine patients with recurrent upper gastrointestinal symptoms were examined during a two year period. Thirty-seven patients had cancer and 62 had benign ulcers as diagnosed by cytology and histopathology. All patients with diagnosis of carcinoma were correctly diagnosed by a combination of the above studies as proven by subsequent surgical exploration of all 37 patients. In the benign group, 23 patients were confirmed by exploratory laparotomy and 16 patients by following up for at least 2 years with upper GI series and/or endoscopy. The highest degree of accuracy in the diagnosis of cancer was achieved by cytology alone (92% of cases) and lowest by barium study of upper gastrointestinal tract (84% of cases). Although the accuracy of endoscopy in detecting cancer of the upper gastrointestinal tract was 86 per cent, 15 per cent of benign ulcers were falsely called neoplastic by this technique. It is concluded that endoscopy with brushing cytology and biopsy is an effective diagnostic tool in distinguishing benign lesions from malignant neoplasms and can be performed with little risk to the patient.

Biopsy↗
PubMedDate not supplied

Positive association of opium addiction and cancer of the bladder. Results of urine cytology in 3,500 opium addicts.

In order to prove the association of opium addiction and cancer of the bladder, an extensive prospective case-control study with urine cytology in all registered opium addicts of Fars province in southern Iran was started in 1975. The urine cytology of the first 3,500 registered opium addicts revealed 15 cases of transitional cell carcinoma, and no cancer was detected among the 1,750 control cases. The crude incidence rate of bladder carcinoma in the general population over 20 years of age in Fars province is 6.6 per 100,000 males per year. The incidence rate among the opium addicts exceeded our expectations; thus, we decided to report the preliminary results of this study. The role of opium as a carcinogen in the bladder and the need for further investigation are discussed. The results of this study strongly suggest the use of routine urine cytology for opium addicts and long-term users of opiate alkaloid for the early detection of carcinoma of the bladder.

Adult↗