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Biomedical subjects

S Belcastro

Publications and source records attributed to S Belcastro.

At least 37 records · Page 2Linked to original sources
PubMed1985

[Severe arterial spasm and secondary thromboses of the limbs in chronic ergotism].

A 40 year old woman who took a daily dose of 2-4 mg of Ergotamine Tartrate (Cafergot) regularly for 6 years to combat persistent migraine, was treated for a non-atherosclerotic arterial disease, severe arteriospasm of the great limb arteries, hyperplasia of the intima and segmental thrombosis. Binding of adrenergic alpha and beta receptors was investigated. Surprisingly it was found that the number of adrenergic beta receptors was significantly lower thant that of a healthy woman of the same age used as a control while the number of alpha receptors was not significantly different. This action of ergotamine on beta receptors could be explained by a dopamine-mimetic stimulation, due to the central nervous system, that could lead to the preferential regulation of beta receptors rather than alpha receptors, almost as a protective mechanism of alpha receptors.

Adult↗
PubMed1984

[Intra-operative manometry and hiatal hernia].

Personal experience of the intra-operative use of oesophageal manometry in cases of hiatus hernia is presented. Using this system the pressure in the air cushion surrounding the L.E.S. can be adjusted to avoid any complications due to overtight or overlax surgery. Various types of post-operative tests confirm the value of the technique.

Esophagoscopy↗
PubMed1978

[Hemodynamics in venous diseases of the lower limbs].

Venous diseases of the lower extremities have been studied haemodynamically by analysis of variations in dynamic venous pressure, which is held to be a fundamental parameter. Pressure modifications point to the state of the deep venous system, the valves and the subfascial communicating veins or to the efficiency or otherwise of the muscular pump of the lower extremities. The venous pressure curve is a reliable indicator of the various clinical stages of chronic venous insufficiency and postphlebitis syndrome. As a clinical parameter, venous pressure is sensitive to all pathological changes in the venous system of the lower extremities. It presents variations proportional to the gravity of pure phlebopathies and of venous diseases secondary to congenital dysplasias (e.g. Klippel-Trenauny syndrome) and to congenital or acquired arteriovenous shunts. An attempt is made to classify venous diseases of the lower extremities on the basis of this parameter and examples are given of dynamic venous pressure curves encountered in the various disease pictures observed.

Chronic Disease↗
PubMed1978

[Echography in the diagnosis of aneurysms of the abdominal aorta].

The principles of echography and its technique are briefly explanded, and 8 personal cases examined for suspected aneurysm of the abdominal aorta are presented. Correct and accurate diagnosis was obtained in cases. In 1 case, aortography was also performed, though its findings were less clear. It is felt that the applications of echography can usefully be extended to the screening, diagnosis and control of this form.

Aorta, Abdominal↗
PubMed1976

[Isolated obliteration of the popliteal artery. Angiographic, functional and surgical considerations].

31 patients suffering from isolated obliteration of the popliteal artery were selected for reporting from a series of 1500 peripheral angiographies. It is pointed out that the lesion is due principally to a segmentary localization of atherosclerosis. A case of adventitial cyst and one of muscular pincer syndrome have also been encountered. Attentive study of angiographic pictures showed up a number of behaviour modalities of the collateral circulation. The surgical approaches available in such circumstances are also reported.

Adolescent↗
PubMedDate not supplied

Thrombosis of the superior vena cava due to a central catheter for total parenteral nutrition.

Total parenteral nutrition (TPN) today is a fundamental procedure in the treatment of critically ill patients, especially if they have serious gastrointestinal diseases. However, use of the central venous catheter is connected with a very important morbidity. At the "Istituto di Patologia Chirurgica" and at the "Intensive Care Unit" of the University of Ferrara, we analyzed 59 cases of deaths from different diseases, on whom a postmortem examination had been performed. Twenty-seven patients had had no central venous catheter: none of them presented thrombosis of the central veins. Thirty-two patients had had a central venous catheter for TPN: five of them presented thrombosis of the central veins at the post-mortem examination. Except for one case who had thrombosis connected with a carcinoma of the right main bronchus, four cases (12.9%) presented thrombosis due to the central venous catheter. The subclavian vein seems to be more commonly connected with thrombosis than the jugular vein.

Adult↗