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Biomedical subjects

S Ben-Meir

Publications and source records attributed to S Ben-Meir.

6 recordsLinked to original sources

Children with schizophrenia spectrum and depressive disorders: a comparative study of premorbid adjustment, onset pattern and severity of impairment.

Premorbid adjustment, onset patterns, and severity of impairment were examined in 66 child psychiatric inpatients with diagnoses of schizophrenia, schizotypal personality disorder, major depression, and dysthymic disorder. When compared to children with depressive disorders, schizophrenic and schizotypal children showed poorer premorbid adjustments, lower IQs, greater impairment at hospitalization, and more chronic dysfunctions. Similar developmental patterns were found for children with schizophrenic and schizotypal disorders, and for children with major depression and dysthymic disorders. The findings underscore the severe impairment in social adaptation shown by schizophrenic and schizotypal children and the relatively good premorbid adjustments of most depressed children.

Achievement↗

Parental communication deviance in childhood onset schizophrenia spectrum and depressive disorders.

Rates of parental communication deviance (CD) were compared in children with schizophrenia and schizotypal personality disorder and in contrast groups of children with major depression and dysthymic disorders. Results indicated significantly higher rates of CD in parents of schizophrenic and schizotypal children than in parents of children with major depression and dysthymic disorders. Schizophrenic and schizotypal children from high CD families showed the most severe impairments and the poorest attentional functioning. However, the small number of schizophrenic and schizotypal children with low CD parents underscored the strong association between schizophrenia spectrum disorders, parental CD and psychosocial and attentional impairment in the child.

Attention↗

Overt hemolysis in patients with glucose-6-phosphate dehydrogenase deficiency: a survey in general practice.

The records of 129 patients with glucose-6-phosphate dehydrogenase deficiency from two general practices were reviewed for overt hemolysis. There were 25 such cases: 14 were diagnosed as favism; 10 were associated with various combinations of drugs, or with fever, infection, acidosis or the neonatal state; and one was of undetermined cause. Over the years 1952-72, these patients had been challenged on 756 occasions with potentially hemolytic drugs. The low incidence of overt hemolysis after antipyretic preparation is noted, as is the danger of nitrofurantoin. The clinical setting was an important determinant of whether hemolysis would occur after drug administration. Fever seemed to be a particularly significant factor. Quantitative determinations of enzyme activity in 18 patients confirmed the reliability of the screening method used. There was no correlation between the enzyme levels and the occurrence of overt hemolysis.

Adolescent↗