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Biomedical subjects

S Beolchi

Publications and source records attributed to S Beolchi.

8 recordsLinked to original sources

[Vulvo-vaginitis in pediatric age].

In pediatric gynecology, inflammatory vulvo-vaginitis are very common. Their diagnosis cannot be based either on the symptoms (itching or pain) or on the signs (leucoxanthorrhea) for these classifications are "non-specific". At the Consulting Room of pediatric gynecology of the Vittore Buzzi Hospital, 215 "non-specific" vulvo-vaginitis cases have been analyzed through bacteriological and microscopical examinations of vaginal secretions. The vaginal tampon resulted negative in 53% of the cases and positive in the remaining 47%. Comparing these results with microscopical examinations we obtain: 81.8% of sensibility, 77.4% of specificity, 87.8% of negative predictive value and 62.2% of positive predictive value. In particular, this last figure is influenced by the high number of false positives of the vaginal tampons, due to the growth "in vitro" of opportunist germs momentarily quiescent "in vivo". Thus it is useful to associated the microscopical examination (that will indicate all the cases in need of treatment) and the bacteriological examination (that will indicate the right cure).

Adolescent↗

Acute urinary retention due to didelphys uterus associated with an obstructed hemivagina in a 5-month-old infant.

A double uterus associated with an obstructed hemivagina is a rare malformation syndrome that has been described in about one hundred cases in the world literature. The malformation is diagnosed after menarche because of symptoms caused by hematocolpos or hematometra, and it is occasionally associated with ipsilateral renal agenesis. In the case described here, the malformation was symptomatic when the patient was 5 months old, and was associated with ipsilateral renal hypoplasia. The clinical and etiologic implications are discussed.

Abnormalities, Multiple↗

Follow-up results of a prevention program for cervical cancer.

Of 4,782 women attending a colposcopy clinic from 1964 to 1971, 4,358 were included in a prevention program for cervical cancer and were followed for at least ten years. Of them, 1,105 were untreated and 3,253 treated. One hundred two underwent surgery and 3,151, electrocautery (ECT). On the basis of the post-ECT colposcopic examination, cervices were divided into iodine dark and iodine light. One cervical intraepithelial neoplasia (CIN III) and three invasive cancers were found among the untreated women. Three neoplasias (one adenocarcinoma, one in situ carcinoma and one invasive carcinoma) were found among the treated non-CIN women, only one carcinoma among the treated CIN women and no neoplasias among the surgically treated women. The comparison showed a difference in favor of the treated group, though it was not statistically significant. A comparison between the observed and expected data on the basis of the literature was highly significant: the expected appeared high. While these data do not prove the basic hypothesis that ECT has a protective effect in cancer prevention, they do provide some evidence in favor of it.

Atrophy↗

Age-related frequency of viral lesions and their association with uterine cervical intraepithelial neoplasia.

Data collection forms of 50,165 routine smears were examined, and of these 47,577 were considered for this study. Viral cytological lesions (VL) were observed in 101 cases: of these, 19 were associated with cervical intraepithelial neoplasia. The total frequency of VL was 0.21%, with the peak in the teenager group (0.49%). The frequency of CIN among VL showed an overall frequency of 18.8%: this was null under 21 years of age and highest (50%) between 51 and 60 years of age. The frequency of VL in relation to clinical provenance of patients and the season of the year did not attain significance.

Adolescent↗

[The biochemical screening of Down's syndrome].

Since the initial observation of an association between low maternal serum aFP and trisomies noninvasive for chromosomal abnormalities is an obvious goal of genetics and obstetricians. Here are reported the results of a biochemical screening for fetal trisomies study based on the dosages of maternal serum aFP, bHCG and uE3 at 16 week gestational age on 1166 pregnant women without risk factors for genetical abnormalities. Sensitivity, positive predictivity and negative predictivity of the screening were 50%, 42.86% and 99.74% respectively.

Adult↗

[The need for urodynamic tests].

Two hundred forty women were studied, who underwent symptomatological anamnesis, clinical examination and urodynamic investigations for female urinary incontinence. Our aim was to distinguish among the three main forms of incontinence (stress, urge and mixed incontinence). When only symptomatological anamnesis is considered, there is an incidence of error in nearly a third of the cases and, when further factors like menopause, prolapse and parity are considered, the incidence of error does not reduce. A correct diagnosis can be determined only by a combined use of clinical assessment and urodynamic investigations. (As regards clinical examination, a positive stress test leads to a diagnosis of stress incontinence. As regards urodynamic investigations a cystometry positive for instability of the detrusor muscle leads to a diagnosis of urge incontinence. If both clinical examination and urodynamic investigations are positive, the diagnosis is of mixed incontinence.) Our findings suggest that routinely it is sufficient to execute only cystometry among urodynamic investigations.

Adult↗