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Biomedical subjects

S Bergonzi

Publications and source records attributed to S Bergonzi.

32 records · Page 2Linked to original sources
PubMed1981

[Radiological diagnosis in 229 cases of breast fibroadenoma].

From 1976 to 1977, 705 patients with a fibroadenoma of the breast, histologically proven by biopsy, were observed at the Istituto Nazionale Tumori of Milan. In 229 cases, the clinical examination was followed by mammography or xeromammography; in 65/229 patients telethermography was also carried out. The aspects of fibroadenoma at x-ray examinations are described together with the difficulties to reach an exact diagnosis: the cases in which a false positive diagnosis of cancer was done are emphasized.

Adenofibroma↗
PubMed1980

[X-ray diagnosis of neoplastic breast calcifications after radio- and chemo-therapy (author's transl)].

The morphological aspects of calcifications in inoperable breast cancers were investigated through repeated mammographic examinations before and after radiotherapy and/or chemotherapy. Aim of the study was to find out the modifications induced by therapy. Different radiological patterns observed during treatment and follow up are described in details. Some findings concerning calcifications, such as modifications of number, distribution, size and shape or new evidence of micro- and macro-deposits are analyzed and discussed. A correlation between radiological findings and clinical response to radio- and chemo-therapy is attempted, but wider experience and information are needed.

Breast Neoplasms↗
PubMed1979

Nipple discharge as a sign of preneoplastic lesions and occult carcinoma of the breast: clinical and galactographic study in 103 consecutive patients.

A clinical and galactographic investigation was carried out on 103 patients with hematic, serous-hematic, and serous nipple discharge. The age of the patients ranged from 18 to 72 years. A single papilloma was found in 20 cases, diffuse papillomatosis in 2 cases, atypical ductal hyperplasia in 8 cases, and ductal carcinoma in 4 cases (3 of these were infiltrating and 1 was noninfiltrating associated with a diffuse papillomatosis). Mammography gave no indications of carcinoma in any of the 4 cases. In the remaining 49 patients, pictures of ductal hyperplasia, periductal mastitis or sclerosis, sclerosing adenosis, or ductal ectasia were observed. The various types of lesions were often associated. Lacunae, stenosis, or occlusion of the ducts, evidenced by galactography, correlated well with the histologic findings of proliferative lesions of the ductal epithelium. Nevertheless, in practice, it should be the type of discharge that indicates surgery rather than galactographic or cytologic data, which appeared to have little diagnostic value. The frequency with which preneoplastic (or limit) lesions, and also nonsuspect carcinomas were found in patients with a significant nipple discharge confirm the importance of this symptom for a secondary prevention of early diagnosis of mammary neoplastic lesions originating from galactophorous ducts. Finally, complete resection of the galactophorous ducts must be considered as the best treatment in all patients with a suspicious nipple discharge that requires surgery.

Adult↗
PubMed1979

[X-ray diagnosis of malignant breast calcifications. (author's transl)].

The authors have taken into consideration the different features of malignant breast tumor calcification. Frequent, rare and extremely rare radiological pictures will be shown and a differential diagnosis with benign micro-calcifications will be considered. A correct mammographic and xerographic technical performance is absolutely necessary to enhance the images of the smallest micro-calcifications. At last we assess the importance of a radiographic control of the surgical blocks, after conservative surgery of the breast, to assure a complete removal of microcalcifications.

Breast Diseases↗
PubMed1976

[Role of thermography in the diagnosis of breast neoplasms].

319 cases of breast pathology of doubtful clinical diagnosis were studied by means of thermography and mammography, with histological verification: 214 proved to be malignant tumours and 105 benign. The role of thermography is discussed on the basis of these results; it would appear to be restricted to diagnostic aid status associated with other procedures, particularly clinical examination and mammography.

Adenocarcinoma↗
PubMedDate not supplied

Lobular breast cancer: how useful is breast magnetic resonance imaging?

RATIONALE AND OBJECTIVES: To review magnetic resonance imaging (MRI) findings in lobular breast carcinoma, the in situ or infiltrating subtype, with special attention to the dynamic curves with the aim to evaluate possible differences with ductal carcinoma. METHODS: In 2 years, 27 patients with lobular and one with tubular carcinoma underwent MRI at the Istituto Nazionale Tumori of Milan. RESULTS: All lobular carcinomas demonstrated early or late enhancement (100% sensitivity), without significant differences in morphology compared with ductal carcinoma, but frequently with a different shape of the dynamic curves. CONCLUSIONS: Due to its infiltrative growth associated to only limited connective tissue reaction, lobular carcinoma often encounters difficulties in mammographic diagnosis. In contrast, MRI can be very helpful in evaluating the true extension of the disease, especially when breast conservation is considered. Due to a more consistent fibrotic stroma, these lesions sometimes show a delayed enhancement, which suggests that more than one set of subtracted images should be evaluated during MRI analysis.

Breast Neoplasms↗
PubMedDate not supplied

Hysterosalpingography in the sequels of conisation of the uterine cervix.

A hysterosalpingographic survey was made of 65 women of reproductive age who had undergone conisation of the uterine cervix for carcinoma in situ or severe dysplasia at least one year before. None of the patients investigated radiologically had undergone uterine surgery before conisation. In a high percentage of cases morphological changes of the cervical canal and, less frequently, the isthmus were found. Most of the changes are attributable to scar retraction, and the hysterosalpingographic findings did not differ appreciably from those following other types of gynecological surgery, namely, segmental or total stenosis and ectasia of the cervical canal and isthmus. A control series of patients with preoperative and postoperative hysterosalpingograms is now under consideration to confirm the radiological findings and to correlate them with clinical data.

Carcinoma in Situ↗
PubMedDate not supplied

[Microcalcifications in the diagnosis and follow-up after the primary chemotherapy of breast neoplasms].

Since 1998, at the National Cancer Institute (Milan, Italy), a study has been carried on relative to primary chemotherapy for locally advanced breast cancers (greater than 3 cm diameter). Aim of the study is to obtain tumor reduction and thus allow a conservative treatment to be performed. The measures of the two greatest diameters of the tumor by means of mammography, at diagnosis and after chemotherapy, are important parameters for treatment planning. Among the 213 patients who completed the whole diagnostic-therapeutic procedures by December 1990, the authors chose 94 cases (44%) presenting breast cancers with microcalcifications and reviewed the relative mammograms. The review was aimed at analyzing morphology, number and extent of the microcalcifications and at assessing their value as reliable parameters of cancer response to primary chemotherapy. In their experience, the authors found that increased visibility of the microcalcifications after chemotherapy is often due to a reduction in both edema and lesion opacity. On the contrary, fewer microcalcifications may be correlated with incisional diagnostic biopsies. In conclusion, if microcalcifications are a useful parameter for diagnosis, they alone are less important when evaluating response to primary chemotherapy, since they probably represent a permanent sign of the extent of the primary lesion. All follow-up mammograms of the patients who underwent conservative surgery were also reviewed: no residual microcalcifications or other suspicious abnormalities were observed.

Adult↗
PubMedDate not supplied

[Angiosarcoma of the breast: mammographic and thermographic study of 4 cases].

At Istituto Nazionale Tumori of Milan four patients with histologically proven angiosarcoma of the breast were evaluated by mammography and telethermography. This is a highly malignant rare tumor which occurs more frequently in young women. The authors outline that only 90 cases have been reported in the literature (once radiologically described in 1966) and analyze clinical and especially mammographic and thermographic signs. Radiological findings simulate those of filloiden tumors or giant fibroadenomas while thermographic patterns show a nearly generalized high hyperthermia. Therefore both methods should be associated for early diagnosis and improvement of the prognosis.

Breast Neoplasms↗