PubMed Health⌕ Search

Biomedical subjects

S Bettini

Publications and source records attributed to S Bettini.

At least 37 records · Page 2Linked to original sources

Leishmaniasis in Tuscany (Italy): VI. Canine leishmaniasis in the focus of Monte Argentario (Grosseto).

The results of a survey of canine leishmaniasis in the coastal focus of Monte Argentario (Tuscany, Italy) are reported. Of the 171 dogs examined, 41 (23.9%) were positive in the fluorescent antibody test (FAT), but only 12 (7.0%) were positive by microscopic observation of lymphatic ganglia. Of the 41 FAT positive dogs, 17 (10.0%) showed signs of the disease. The evolution of leishmaniasis over one year from the first examination showed that 88.0% of the dogs with signs died of the disease, and 36.0% of the asymptomatic dogs became patent or died; 52.0% of the asymptomatic dogs had apparently recovered. The prevalence of the disease, the geographical, age, sex and race distribution of cases, the evolution of leishmaniasis in dogs and FAT positivity are discussed.

Animals↗

Leishmaniasis in Tuscany (Italy): (II) Leishmania from wild Rodentia and Carnivora in a human and canine leishmaniasis focus.

From April 1977 to February 1978, wild mammals were trapped in a focus of low leishmanial endemicity (Baccinello) in the Province of Grosseto (Tuscany, Italy). Spleen homogenates of the trapped animals were injected i.p. into hamsters, from which spleen biopsies were taken after 60 days and impression smears carefully observed for the presence of Leishmania. Positive spleens were subinoculated into hamsters. 404 animals of 12 species were trapped: 31 insectivores, 317 rodents and 56 carnivores. Black rats (Rattus rattus) and field mice (Apodemus sylvaticus) were the rodent species most frequently trapped--160 and 139 respectively--of which 143 and 134 respectively were tested in hamsters for Leishmania. 35 foxes (Vulpes vulpes) were caught, of which 16 were tested for Leishmania. Four hamsters were found infested with Leishmania. Three of them had been injected with spleen homogenates from R. rattus and one from V. vulpes although liver and spleen impression smears of all trapped animals were negative for Leishmania on direct microscopical examination. The significance of Leishmania infection in wild animals in the leishmanial focus of Baccinello is discussed.

Animal Population Groups↗

Leishmaniasis in Tuscany (Italy): (I) An investigation on phlebotomine sandflies in Grosseto Province.

A survey of phlebotomines has been made in the area of the Province of Grosseto (Tuscany, Italy) where human cases of both visceral and cutaneous leishmaniasis have recently occurred. 12 collecting stations, placed around the leishmaniasis foci, were divided into three groups of localities, the Argentario Promontory, coastal plains territory and hilly inland territory. Sandflies were collected with lit and unlit oil traps, and by hand. A total of 11,032 specimens (57% males) were caught and identified. Of these, 86.6% were Phlebotomus perfiliewi, 10.8% P. perniciosus and 2.3% Sergentomyia minuta; only a few specimens were P. papatasi and P. mascittii. In the first group of localities, P. perniciosus was very abundant (87.8%) and S. minuta scarce (12.0%); in the second group, P. perfiliewi was the only species collected; in the third group, P. perfiliewi was very abundant (98.0%), S. minuta was vert scarce (1.1%) and P. perniciosus even more so (0.7%). P. perniciosus is thought to be the probable vector of visceral leishmaniasis in the area of the Monte Argentario and P. perfiliewi is strongly suspected of playing a role in transmission of the cutaneous form in the third group of localities. The species responsible for transmitting visceral leishmaniasis in some of the foci in this area is yet to be found.

Animals↗

Studies on Mediterranean leishmaniasis: V.A. preliminary epidemiological survey of human leishmaniasis in Tuscany.

Leishmanin skin testing was performed on 1,285 people in the Tuscany region of Italy. In a known endemic area for leishmaniasis there was an increasing positivity with age, while in another area the curve was bell-shaped suggesting an interruption of transmission in the recent past. In all areas the positivity rate for males was higher than for females, but it was not possible to distinguish between areas of cutaneous and visceral disease.

Age Factors↗