Biomedical subjects
Publications and source records attributed to S Bhushan.
Semen analysis of 66 unmarried medical students in the age group of 17-21 years was carried out. A higher liquefaction time pH, motility, lower sperm count and abnormal forms were observed compared to reported values. Liquefaction time, pH and sperm count was found significantly different in non-vegetarians and vegetarians, perhaps due to difference in their dietary proteins.
The effect of raw garlic on normal blood cholesterol level in males of the age group of 18-35 years was studied. The subjects, who never ingested garlic before, were given 10 g of garlic daily with their diet for two months. Fasting blood samples were investigated in respect of cholesterol before and after two months of garlic intake. Initially the blood cholesterol level ranged between 160-250 mg% which decreased significantly in all the subjects of experimental group after two months of ingestion of garlic. The slight decrease or increase in the blood cholesterol level of control group was not significant. The raw garlic can be advocated for daily ingestion in order to lower one's blood cholesterol level even if it is within normal limits.
183 students of 17-22 years age group were studied in respect of fluid intake, urine output and urine titratable acidity under normal conditions for two consecutive days. The study was performed in early winter in eastern part of U.P. Male students were observed to have higher fluid intake and urine output as compared to female. Average fluid intake and urinary output in male students were observed to be 2860 S.D. +/- 780 ml and 1860 S.D. +/- 880 ml respectively while corresponding readings for female students were 1980 S.D. +/- 390 ml and 1550 S.D. +/- 840 ml. Titratable acidity was observed to be high with a mean of 47.46 meg S.D. +/- 16.2 meq as compared to commonly accepted average range of 25-35 meq. Nonvegetarian subjects were found to have significnatly higher titratable acidity. Fluid intake and urine output did not have any significant effect on titratable acidity of urine in both the sexes. Need for further studies on this subject has been stressed.
Daily urinary creatinine excretion and creatinine coefficient of eighty-four healthy medical students have been studied for three consecutive days. Daily creatinine excretion has been observed to be higher in the male subjects compared to the female counterparts. Creatinine excretion has been observed to be dependent on body weight of the subjects. The variability from subject to subject was higher than observed by most other workers. Day to day consistency within the same subject was rather low. Creatinine coefficient was computed per kg of body weight as well as per kg of lean body weight. In both the cases, it has been found to be higher in the males than in the females. Though an important factor, yet body weight of a subject alone could not explain satisfactorily wide variability of creatinine excretion in the present study. The possible influencing factors have been discussed along with clinical implications.