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Biomedical subjects

S Biernat

Publications and source records attributed to S Biernat.

At least 19 recordsLinked to original sources

Ductal sebaceoma (sebomatricoma).

We present a case of an unusual tumour arising in the forehead of a 52-year-old female. The tumour, diagnosed as sebaceoma (or sebomatricoma), showed predominantly differentiation towards ductal protion of the sebaceous gland. It was marked in tissue sections as areas of "poroid" cells and the tumour required differentiation from poroma. Focal areas of necrosis en masse in the present tumour contributed further difficulties in to the differential diagnosis. As single multivacuolar sebocytes were found and no cuticular cells could be identified, the tumour was diagnosed as ductal sebaceoma (sebomatricoma). The aspects of morphological distinction between sebomatricomas and poromas are presented with its clinical implications.

Diagnosis, Differential↗

Cutaneous adnexal carcinoma arising within a solitary cylindroma-spiradenoma.

Malignant transformation within an adnexal neoplasm with features of spiradenoma and cylindroma is reported in a 60-year-old woman. The malignant component of the tumor consisted of areas of solid carcinoma, with focal squamous metaplasia. In the benign component, apart from the features of spiradenoma and cylindroma, sebaceous differentiation was present adjacent to a cystic space lined by apocrine epithelium. The morphologic composition of this unusual neoplasm supports the concept of a histogenetic relationship between cylindromas and spiradenomas, including their differentiation toward the pilosebaceous-apocrine unit.

Adenoma, Sweat Gland↗

Myxoid liposarcoma of the urinary bladder.

We report a case of myxoid liposarcoma of the urinary bladder, that occurred in a 36-year-old woman. We faced the difficulties in reaching the preoperative diagnosis, likewise in determining the extent of the tumor, as the results of the computed tomography differed from the pathologic findings of the tumor. The review of the literature concerning this unusual site for liposarcoma and methods of treatment is also included.

Adult↗

Cutaneous ciliated cyst: a case report.

We report a case of a cutaneous ciliated cyst in the buttock of a 16-year-old girl. We describe the pathological and immunohistochemical data on this very uncommon skin lesion, whose histogenesis remains a matter of controversy.

Adolescent↗

[Immunohematological study of 7 cases of acquired B transformation using anti-B and selected acquired anti-B].

Seven acquired B samples were studied with selected anti-B sera. Eight sera came from group A subjects, four from group O subjects. The anti-B sera reacting with the acquired B antigen are always a mixture of two kinds of antibodies: a fraction that is only reactive with B antigen, another that is cross-reactive with B and acquired B antigens. In some sera, especially those coming from group O subjects, there is, in addition, a potent antibody of polyagglutination for acquired B red cells. The polyagglutinability associated with acquired B red cells is analysed. According to the results obtained using lectins, four red cell samples are merely acquired B, the three others are acquired B + Tk. The polyagglutinability associated with Tk transformation is non sensitive to acetylation of red cells. The polyagglutinability specific for acquired B is sensitive to acetylation but appears complex in itself. According to the reactivity of selected sera for acquired B samples and the studies of inhibition with simple sugars, there are at least two antigens involved. One of them is present in all of the acquired B samples and it is likely to have arisen from the action of a deacetylase on a structure including N-acetylgalactosamine.

ABO Blood-Group System↗