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S Boudaya

Publications and source records attributed to S Boudaya.

16 recordsLinked to original sources
PubMed2006

[Adverse effects of intralesional Glucantime in the treatment of cutaneous leishmaniosis].

OBJECTIVE: The treatment of cutaneous leishmaniasis used in Tunisia is Glucantime. The aim of this retrospective study was to determine the adverse effects of intralesional Glucantime and to calculate the risk/benefit rate of this treatment. RESULTS: Adverse effects were observed in 14 cases (5%). For facial lesions, we observed facial staphylococci in 2 cases, stibio-intolerance in 1 case, and a palpebral subcutaneous nodule in 1 case. In limb lesions the complications were: sporotrichoid nodules in 5 cases, vagal malaise (1 case), pyodermitis (1 case), erysipelas (1 case), necrosis (1 case), and urticaria (1 case). COMMENTARY: The adverse effects of intralesional Glucantime are mostly infections, mainly observed in cephalic localization, and stibio-intolerance. For this reason, intralesional injection of Glucantime must be avoided in the cephalic region.

Adolescent↗
PubMed2006

[Gingival metastasis in breast phyllodes tumor].

BACKGROUND: The metastasis of oral cavity is rare. We report a gingival metastasis in the course of low grade phyllode sarcoma of the breast which is usually little metastatic. CASE-REPORT: A 44 year old woman was operated two years ago for a phyllod sarcoma of the breast histologically confirmed. She presented for a mandibular exophytic tumour associated with haemorrhagic, necrotic, ulcerated and bulking gingivitis surrounding at the level of the maxillary and mandibular gingiva. The examination revealed multiple nodular lesions of the trunk and the scalp. The histological examination confirmed the diagnosis of cutaneous and gingival metastasis of the phyllod sarcoma of the breast. The evolution was rapidly fatal. DISCUSSION: The gingival metastasis are rare tumours with a bad prognostic. Their diagnosis is based on clinical and histological arguments and must be made different from chronic gingivitis which can be associated.

Adult↗
PubMed2005

[Glucantime injection: benefit versus toxicity].

UNLABELLED: Glucantime is the most common stibied derivative used to treat cutaneous leishmaniasis (CL) in Tunisia; however adverse effects have been reported. OBJECTIVES: This retrospective study deals with the various adverse of intramuscular glucantime used for CL. RESULTS: Nineteen patients (21%) receiving intramuscular Glucantime developed adverse effects. 8 male and 11 female patients, mean age 45, ranging from 8 to 84 years were affected. adverse effects were: fever (3), arthralgia and myalgia (4), nausea and vomiting (2), erythema nodosum (1), acute renal failure (3 including 1 lethal case), hepatic cytolysis (1), skin rash (4), and inflammation of the injection site (1). CONCLUSION: Adverse effects of intramuscular Glucantime were relatively frequent in our series. Arthralgia, myalgia, and skin rash were not severe and disappeared when the treatment was stopped. Stibiointoxication cases, mainly acute renal failure, were serious.

Aged↗
PubMed2005

[Penile sporotrichoid cutaneous leishmaniasis].

The localisation of the cutaneous leishmaniasis of L. major at the penis level is rare, we report here a new observation. Mr K. R aged of 41, without known pathological background presented for 20 days a nodular lesion of the anterior face of the neck, 2 juxtaposed ulcerated nodular lesions of the left wrist. He presented also subcutaneous nodules ranged linearly and extended to the root of the penis. Theses lesions were covered by an erythematous or ulcerated skin. The smear made from the genital lesions of the penis confirmed the diagnosis of a cutaneous leishmaniasis. The evolution was favourable after a 21 days treatment by doxycyclin after an interval of one week. Our observation was specific by the localisation of the cutaneous leishmaniasis and by the clinical form. This shows that in our region cutaneous leishmaniasis is characterised by different clinical symptoms.

Adult↗
PubMed2003

[Pemphigoid gestationis: a study of 15 cases].

INTRODUCTION: Pemphigoid gestationis is a rare subepidermal bullous dermatosis generally occurring during the 2(nd) or 3(rd) quarter of gestation or in the postpartum period in women who already have been pregnant. OBJECTIVE: The aim of this work is to draw a profile of the epidemiology, clinical aspects, treatment and evolution of the disease by studying hospital series. METHODS: In this retrospective study, 15 cases of pemphigoid gestationis confirmed by direct immunofluorescence, followed in the department of dermatology between 1983 and 1999, were included. RESULTS: The age of onset was 19 to 39 years (mean age: 30 years). In 73% of cases, pemphigoid gestationis occurred in women who had already been pregnant, and appeared during the last 3 months of gestation in 11 patients. In all cases, purities was the first symptom, followed by a erythematous maculopapular eruption. In the steady state of the disease, all patients had annular confluent erythematous papules with herpes, like vesicles predominant in the umbilicus. The diagnosis of pemphigoid gestationis was confirmed by direct immunofluorescence in all cases demonstrated linear staining of C3 at the basement membrane zone. Systemic corticosteroids (0.5-1mg/kg/day) were used in 54% of reported cases. Dapsone was efficient in 26% of patients. 20% of patients were treated with oral antihistamine and topical glucocorticoid. Recurrence occurred in postpartum in 53,3% of patients. Two patients had recurrence during the following pregnancies. CONCLUSION: PG remains a rare dermatitis of pregnancy. Our series is comparable to the literature: the late occurrence of PG during the course of pregnancy, the high frequency of multigravida women, the lack involvement in the newborn, however with some particularities: the frequent involvement of the face and the efficiency of dapsone.

Adrenal Cortex Hormones↗
PubMed2003

[Eosinophilic pustular folliculitis in infancy: an unusual case].

INTRODUCTION: Eosinophilic pustular folliculitis in children is a follicular inflammatory dermatosis, usually occurring early in life. The disease progresses in flares of prurigenous plaques studded with papules and sterile pustules of the scalp and other areas of the skin. OBSERVATION: A 7 year-old boy presented with itching papular vesicular and pustular plaques on the scalp and the face. Pigmented plaques with pustular border, located on the trunk, were associated with pustular and erosive lesions of the side of the lower lip and in the nostrils. A specimen taken from the pustules did not show bacterial or fungal infection. Histologic examination of a biopsy specimen showed subcorneal pustules with eosinophilic and neutrophilic infiltrates of follicles. Clinical improvement was obtained only by the combination of steroids and dapsone, but recurrence followed withdrawal of treatment. DISCUSSION: Eosinophilic pustular folliculitis in children is rare. Our case report combines features of the infancy form (lesions located on the scalp and face) and the adult form (location on the trunk and limbs with annular distribution), expressing the conceptual confusion that remains between both forms. The mucosal involvement seen in our patient has never been reported in the literature neither in the infancy nor in the adult form.

Biopsy↗
PubMed1998

[Actinic lichen planus: 32 cases].

OBJECTIVES: Actinic lichen planus is a variant form of lichen planus located on light-exposed areas, generally in children or young adults with dark skin living in tropical countries. Three forms have been described: annular, pigmented and dyschromic forms. The aim of this work was to determine the epidemiological, anatomic and clinical features of actinic lichen planus in our region. PATIENTS AND METHODS: A retrospective study included 32 patients with actinic lichen planus on the basis of clinical features and histological findings. The geographical origin, age, sex, phototype and clinical and histological characteristics were recorded for each case. RESULTS: The incidence of actinic lichen planus was estimated at 1 case per million inhabitants per year. Age in our patients ranged from 7 to 47 years (mean = 17 years), with female predominance (F/M = 2.5). Twenty-six patients were from the Sfax area. Phototypes ranged from III to V, mainly type IV (43.7%). Onset was usually in spring (in 18 cases). Facial involvement was the most frequent (91%) and the annular form predominated (84%); the pigmented form was found in 4 patients and the dyschromic form in 1. Histology showed typical actinic lichen planus in 18 cases and lichen planus in 14 cases. DISCUSSION: Compared with data reported in the literature, our series showed a low incidence, younger patients and greater female predominance. The annular form appeared to be the most specific. The pigmented form raises problems of differential diagnosis with melasma. Certain histological signs are highly suggestive.

Adolescent↗
PubMed1998

[Pityriasis versicolor in children: a retrospective study of 164 cases].

INTRODUCTION: Pityriasis versicolor is a superficial mycosis uncommonly reported in children. It occurs frequently in warm humid climates. Clinical diagnosis can be confirmed by mycology examination of a biopsy sample or a patch-test. The aim of our work was to assess the frequency of pityriasis versicolor in children in our region and ascertain the contribution of the cutaneous patch test and its diagnostic specificity. PATIENTS AND METHODS: A retrospective analysis was conducted in patients meeting the following inclusion criteria over a 5-year period: age < 14 years, clinical presentation compatible with pityriasis versicolor, a positive patch-test. Age, sex, clinical features and favoring factors were recorded for all patients. Patch tests were performed in a control group of age-matched children with eczema or vitiligo. RESULTS: Pityriasis versicolor was diagnosed in 1,379 cases during the study period including 164 children (11.8 p. 100). Age varied from 5 months to 14 years (mean 11 years), with a slight female predominance. Facial lesions were the most frequent (n = 78; 47.5 p. 100), preferentially on the forehead (n = 53; 68 p. 100). An achromic and hypochromic aspect predominated (n = 118; 72 p. 100). The adhesive tape tests were negative in all controls. DISCUSSION: Pityriasis versicolor is exceptional in children in our region. The adhesive tape test provides a specific diagnostic tool. Preferential facial localization and predominant achromic and hypochromic aspect are characteristic of childhood pityriasis versicolor in our region. These 2 features are also reported in the literature. Childhood cases suggests the pathogenic factors involved in pityriasis versicolor should be reconsidered. Pityriasis versicolor should be included in the differential diagnosis of childhood hypopigmentation of the face.

Adhesives↗
PubMed1998

[Childhood plaque milia of the inner canthus].

BACKGROUND: Milia en plaque is an uncommon skin condition usually seen in adult women, typically in the retroauricular region. We report a new localization in a young child. CASE REPORT: A 6-year-old girl with an uneventful history had developed over the last 7 months an erythematous plaque with numerous whitish-yellow microcysts on the left internal canthus. No local or general favoring factor was found. Skin biopsy showed numerous cystic cavities with an epidermal lining containing layers of keratin within a moderately inflammatory infiltration. The lesion resolved after enucleation of the cysts and no recurrence has been observed after 9 months follow-up. DISCUSSION: Milia en plaque is a charateristic erythematous lesion covered with cysts. The usual localization is the retroauricular region, but other localizations have been reported, mainly on the head. This is the first report involving the internal canthus and also in such a young child. One case of a 15-year-old boy has been discribed. Milia en plaque is often a primary condition as in our case although local or general factors may rarely be inductive. Our case illustrates the different localizations possible for milia en plaque, with predominance on the head, and the possibility of childhood cases. We prefer the term milia en plaque rather than retroauricular milia en plaque.

Child↗
PubMed1994

[Lyme disease in Sfax].

Primary borreliosis is exceptional in North Africa. From 1988 to 1992, we observed 23 cases (10 females, 13 males; age 20-67 years) of erythema chronicum migrans in our unit. The lesions began during the months of April to October with a peak in July and August. There was always an unique characteristic lesion with a central mark left by the bite in 20 cases. Serological studies were not performed. Several antibiotics were given. Primary borreliosis of the erythema chronicum migrans type are seen in Tunisia and probable throughout North Africa. The clinical presentations and seasonal distribution are the same as in Europe.

Adult↗
PubMedDate not supplied

[Necrobiosis lipoidica - 3 case reports].

Necrobiosis lipoidica is a rare degenerative disease mostly seen on the legs. The association to diabetes mellitus is usual. We report three patients with necrobiosis lipoidica located on the extremities, 2 of them were already treated for diabetes. Necrobiosis lipoidica has distinctive clinical and histological appearances. The lesions appear as well circumscribed, erythematous plaques, with a depressed centre. Some of these lesions may progress to ulcers. The legs are commonly involved. Angiopathy leading to thrombosis of the cutaneous vessels has been implicated in its pathogeny. There is no specific therapy for this disease Topical and/or intralesional corticosteroids are the most widely used treatment.

Adolescent↗