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Biomedical subjects

S Brener

Publications and source records attributed to S Brener.

11 recordsLinked to original sources
PubMed2000

Immediate and delayed effects of treatment at the Dead Sea in patients with psoriatic arthritis.

The purpose of this study was to evaluate the immediate and delayed effects of balneotherapy at the Dead Sea on patients with psoriatic arthritis (PsA). A total of 42 patients with PsA were treated at the Dead Sea for 4 weeks. Patients were randomly allocated into two groups: group 1 (23 patients) and group 2 (19 patients). Both groups received daily exposure to sun ultraviolet rays and regular bathing at the Dead Sea. Group 1 was also treated with mud packs and sulfur baths. Patients were assessed by a dermatologist and a rheumatologist 3 days before arrival, at the end of treatment, and at weeks 8, 16, and 28 from the start of treatment. The clinical indices assessed were morning stiffness, right and left hand grip, number of tender joints, number of swollen joints, Schober test, distance from finger to floor when bending forward, patient's self-assessment of disease severity, inflammatory neck and back pain and psoriasis area and severity index (PASI) score. Comparison between groups disclosed a similar statistically significant improvement for variables such as PASI, morning stiffness, patient self-assessment, right and left grip, Schober test and distance from finger to floor when bending forward. For variables such as tender and swollen joints, and inflammatory neck and back pain, improvement over time was statistically significant in group 1. Addition of mud packs and sulfur baths to sun ultraviolet exposure and Dead Sea baths seems to prolong beneficial effects and improves inflammatory back pain.

Arthritis, Psoriatic↗
PubMed1999

Chest pain--a strong predictor of adverse cardiac events following precutaneous intervention (from the Evaluation of Platelet IIb/IIIa Inhibitor for Stenting Trial [EPISENT])].

Postprocedural chest pain remains a common problem, and irrespective of electrocardiographic changes, is associated with a higher incidence of early cardiac events. A return to the catheterization laboratory is unlikely to benefit patients with postprocedural chest pain without electrocardiographic changes with documented irreversible intraprocedural complications, or those with late postprocedural pain.

Abciximab↗
PubMed1996

Angiographic correlates of cardiac death and myocardial infarction complicating major nonthoracic vascular surgery.

In a case-control study of 63 patients undergoing major nonthoracic vascular surgery with prior cardiac catheterization, we found total coronary occlusion serving viable myocardium and "nonobstructive" lesions to be the most common proximate cause of perioperative myocardial infarction or death. The extent of coronary disease by several measures was significantly correlated with adverse outcome, and prior bypass surgery appeared to be protective.

Aged↗
PubMed1995

Value of tongue biting in the diagnosis of seizures.

BACKGROUND: Seizures are rarely witnessed by physicians, and the diagnosis is usually made on the basis of the history. Tongue biting is classically considered to favor a diagnosis of epileptic seizure. The usefulness of tongue biting in the differential diagnosis of seizures was evaluated. METHODS: A prospective study of the presence of oral lacerations in 106 consecutive patients admitted to our Epilepsy Monitoring Unit and a retrospective study of a population of 45 patients with syncope were performed. The relationship between tongue biting and diagnosis (epileptic vs nonepileptic events) was analyzed. RESULTS: Of the 106 monitored patients, 63 had episodes characterized by bilateral motor activity, complete loss of consciousness, or both; 34 patients had epileptic seizures, while 29 patients had exclusively nonepileptic episodes. Eight patients suffered an oral laceration; all involved the side of the tongue, and all had documented epileptic seizures. Of the 45 patients with syncope, in only one was the tongue lacerated, and this was at the tip. Tongue biting had a sensitivity of 24% and a specificity of 99% for the diagnosis of generalized tonic-clonic seizures. Lateral tongue biting was 100% specific to grand mal seizures. CONCLUSION: Tongue biting, particularly if it is lateral, is highly specific to generalized tonic-clonic seizures.

Adolescent↗
PubMed1994

[Hemotherapy and transfusional Chagas' disease in Brazil].

With the increased presence of Chagas' disease in urban areas and the rising importance of transfusional transmission of Trypanosoma cruzi, a proper and realistic approach to hemotherapeutic treatment has become crucial in Brazil. Bringing together data from various institutions, this study analyzed hemotherapy and the problem of transfusional Chagas' disease in 850 Brazilian municipalities from 1988 to 1989. It was found that some type of hemotherapy was practiced in 68.8% of these municipalities at the time, this practice being qualitatively and quantitatively proportional to the population size of the municipality. The official blood bank system supplied the blood used in 13% of these services. In relation to prevention of the main diseases transmissible by transfusion, prior screening of donors was carried out by 75.2% of the services for syphilis, 65.4% for hepatitis, 53.8% for AIDS, and 66.9% for Chagas' disease. These percentages vary by region and by size of the municipality. The majority of donors are classified as voluntary, with only 2% categorized as paid donors. In the case of Chagas' disease, most services used only one serologic technique to screen donors, most commonly hemagglutination or immunofluorescence, while only 10.3% of services had previous experience with chemoprophylaxis using gentian violet. The proportion of potential donors with positive serology for anti-Trypanosoma cruzi antibodies was around 1%. These data were confirmed by information from blood banks and Brazilian hemotherapy professionals.

Blood Banks↗