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Biomedical subjects

S Bruseth

Publications and source records attributed to S Bruseth.

6 recordsLinked to original sources
PubMed1993

[Mistletoe in the treatment of cancer].

Mistletoe (Viscum album) was introduced in the treatment of cancer in 1917. Today, extracts from the plant are used in adjuvant cancer therapy mainly as injections. The most important active agents are lectins, which have cytotoxic and immunostimulating effects. Mistletoe extracts have low toxicity. No fatal side effects have been reported. More than 40 clinical studies have been carried out, mainly at the Lukas Klinik in Switzerland and the Ludvig Boltzmann-Institute in Austria. Most of these studies claim that mistletoe has a positive effect, but were of poor methodological design. Therefore, in the light of our own positive experiences, we recommend a randomized multicentre study to evaluate the effect of mistletoe in cancer treatment.

History, 20th Century↗
PubMed1991

[Effect of Arnica D 30 during hard physical exertion. A double-blind randomized trial during the Oslo Marathon 1990].

The effect of Arnica Montana on stiffness, restitution time and cell damage during hard physical exercise was evaluated in a randomized double blind trial during the Oslo Marathon. 36 participants were randomized: one group received Arnica 10(-30) five pills twice daily for five days, starting the day before the event. The other group received placebo pills. Blood tests were carried out before and immediately after finish, and after 48 and 72 hours. Stiffness was evaluated on a visual analogue scale after finish and on the next three days. There was no difference between the groups as regards ALAT, ASAT, GT, LD, creatinine, haptoglobin or magnesium. CK increased in both groups, but to a higher level in the placebo group. The difference was greatest on the second day (p = 0.07). A feeling of stiffness was more pronounced in the placebo group on all four occasions (p = 0.06 and 0.07 on day 2 and 3). There was no indication that Arnica reduced the time of restitution.

Adult↗
PubMed1991

[Homeopathy--the past or a part of future medicine?].

The exact mechanism for the effect of homeopathic remedies is still an enigma. Research shows in vitro effects of homeopathy, as well as differences between the effects of simple dilutions and so called homeopathic potencies. Some of the (relevant) publications are widely disputed. More than 100 controlled clinical trials in humans have been published, but the quality of the majority of the studies is not acceptable. However, some good quality studies do show an effect of homeopathic medicine. We therefore recommend further studies and propose a model for study design. No serious side effects have been reported from homeopathic medicine.

Clinical Trials as Topic↗