Biomedical subjects

S Bruvik

Publications and source records attributed to S Bruvik.

2 recordsLinked to original sources

PubMed2000

[Use of methadone in the treatment of psychotic patients with heroin dependence].

Comorbidity of psychosis and substance abuse has gained increased attention for some time. However, pharmacological treatment for opioid dependence among psychotic patients is seldom described. We present the treatment of four opioid dependent psychotic patients with methadone and antipsychotic medication. Three of the four patients had initially a period of increased psychotic symptoms, but all four patients have shown marked improvement following the introduction of methadone. Compliance with treatment has increased, they have had enduring non-psychotic periods and a markedly reduced use of illegal substances. The results should obviously be interpreted with caution, given the small number of subjects. Further research is therefore important.

Adult↗

PubMed1999

[The Oslo methadone project].

Of a total of 161 patients referred to a high threshold methadone project, 50 patients with an average age of 37 years and more than ten years of heroine use were included. Retention was 72% after three years, none had died by overdoses during methadone treatment, and criminality and prostitution were negligible. The overdose mortality was significantly reduced compared to those on waiting list while the difference in mortality from all causes was less convincing. Drug-taking continued for a considerable portion of the patients, and continued control and follow-up was necessary. Methadone cannot replace other types of treatment, but is a valuable contribution when such treatment is integrated in a comprehensive management. Active rehabilitation efforts are essential.

Adult↗