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Biomedical subjects

S Bryan

Publications and source records attributed to S Bryan.

78 records · Page 5Linked to original sources
PubMed1982

Studies on two novel angiotensin II actions.

Animal data suggest that angiotensin II may directly affect renal sodium retention independent of aldosterone (4,6). Additionally there is evidence to suggest that the hormone can stimulate protein synthesis in a variety of tissues and that indeed it may be a vasculotoxin (5,7). We describe here experiments designed to elucidate the role of angiotensin II in renal sodium retention in normal man. Additionally we present preliminary evidence suggesting that unlike the rapid sodium retaining effect, some delayed (trophic) actions of the hormone may be generated by a hitherto unappreciated mechanism.

Adult↗
PubMed1976

Effect of oral contraceptives on rhythmic urinary metal excretion.

Thirteen women, six of whom were using oral contraceptive agents, between the ages of 23 and 34 years, free from illness, and without a previous clinical history of menstrual abnormality, were studied with chronobiological methods for circadian (about 24 hour) patterns of metal and creatinine excretinine excretion. Circadian rhythms were detected for the excretion of lithium, potassium, iron, sodium, copper, and creatinine. Statistically significant by lower 24 hour excretion (mesors) of lithium, potassium, and iron was detected for the subjects using oral contraceptive agents. Although all women adhered to nearly identical activity-rest (synchronization) schedules, the peak times (acrophases) of the metal excretory rhythms for oral contraceptive users were phase delayed by about two hours.

Adult↗
PubMedDate not supplied

The effect of PACS on the visualization of the lateral cervical spine and the management of patients presenting with trauma.

In patients presenting with trauma, early diagnosis of neck injuries is likely to affect long-term outcome. This paper reports a study that compared lateral images of the cervical spine produced by a Picture Archiving and Communication System (PACS) with the same images produced using computed radiography (CR). The study was undertaken at the Hammersmith Hospital, London. Data were collected on 100 patients who presented with trauma. Both soft copy (PACS) and hard copy (CR) images of the cervical spine were produced for each patient from the same radiographic exposure. The images were viewed by five clinical members of the Accident and Emergency Department. Data were collected on the level of the cervical spine that could be viewed, the clinical management following the viewing of the image and the use of PACS 'tools'. Overall no statistically significant differences between modalities were found in the level of visualization. Within viewer differences were found for three viewers: one indicating better visualization with PACS and two indicating better visualization with CR. The results relating to patient management indicate greater clinician confidence following the viewing of PACS images for two viewers. The use of PACS 'tools' improved visualization of the cervical spine for one viewer.

Adult↗