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Biomedical subjects

S Buchs

Publications and source records attributed to S Buchs.

17 recordsLinked to original sources
PubMed1984

[Lethality and danger of 14 types of purulent meningitis in the pre-ampicillin and in the ampicillin period. Synoptic overview of an epidemiologic study].

UNLABELLED: Based on epidemiological data in the western literature, the lethality of purulent meningitis over the last 32 years has been assessed. 14 types of meningitis (11 with frequent, 3 with rare etiologic agents) were investigated, and the results of the pre-ampicillin period (1948-1962) compared with the post-ampicillin period (1963-1979). RESULTS: during the ampicillin period lethality decreased significantly in patients aged below 60 years. For meningitis caused by salmonellae and certain strains of streptococci, the decrease was not statistically significant. In the population over 60, however, no significant decrease occurred, and the lethality of meningococcal meningitis even increased significantly. Presentation in graph form shows these findings very clearly, and comparison with the lethality of Hemophilus influenzae meningitis serves to express the potential danger of all these meningitis types numerically.

Adolescent↗
PubMed1984

[Enterococcal meningitis].

104 cases of enterococcal meningitis from the literature of the last 35 years have been reviewed: 70% are pediatric patients, 30% are adults. Malformations or concomitant conditions favour the outbreak of the disease. Mixed infections are frequent (15%). The average lethality is about 40% with a variation of +/- 22% depending on the patients prior state of health. Treatment is still very difficult even with the latest antibiotics.

Adult↗
PubMed1983

[Mortality of rare purulent meningitis, (Staphylococcus, Listeria Pseudomonas, Proteus, Klebsiella, E. coli, Salmonella). An epidemiologic study using the literature from the last 30 years].

3056 cases of purulent meningitis caused by seven rare microorganisms (Staphylococci, Listeria, Pseudomonas, Proteus, Klebsiella, E. coli, Salmonella) were collected from the West European and North American literature of the last 30 years. The average lethality has been calculated for the periods ranging from 1948 to 1962 and from 1963 to 1979 in order to compare the results due to the use of penicillin and older antibiotics with those accomplished with ampicillin and the aminoglycosides. After 1963 the death-rate of each type of meningitis decreased considerably (except for Salmonella meningitis): the lethality of the whole group fell from 48% to 33%, in the subgroup of gram-negative meningitis from 55% to 38%, and in the group of neonatal gram-negative meningitis from 67% to 52%. The best results were seen in Proteus meningitis where lethality decreased from 55% to 15%. In E. coli meningitis there was a reduction from 60% to 43% only. Using the chi-square test all these differences were highly significant (p less than 0.001).

Adolescent↗
PubMed1977

[Course, prognosis and therapy of enterococcal meningitis as compared with other streptococcal meningitides].

Seventy-five cases of enterococcal meningitis and 182 cases of meningitis caused by other streptococci are collected from the literature and discussed. Enterococcal meningitis occurs preferentially in debilitated patients at the extremes of life, i.e. in infants, small children and the elderly sick. Streptococcal meningitis, by contrast, may occur at any age in infected individuals. Enterococcal meningitis not uncommonly occurs in the presence of mixed infections. Residual defects following recovery are found in both forms of the disease even where therapy was apparently adequate.

Adolescent↗