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Biomedical subjects

S Burrows

Publications and source records attributed to S Burrows.

At least 55 records · Page 3Linked to original sources

The postmortem examination. Scientific necessity or folly?

Review of 252 autopsies on adult inpatients showed substantial differences between the major postmortem findings and the clinical diagnoses in 30 cases (11.9%). The clinical errors in at least half of these patients were of academic interest only. Errors in the diagnosis of malignant neoplasm occurred in 29 (25.7%) of 113 patients with cancer; however, all but three (2.7%) were of academic interest only. The results indicate that current diagnostic techniques may have decreased the value of the "routine" autopsy. Greater stress should be placed on the postmortem examination in selected cases rather than in a fixed percentage of deaths.

Adult↗

Serum gamma-glutamyl transpeptidase. Evaluation in screening of hospitalized patients.

Evaluation in screening of hospitalized patients. Am J Clin Pathol 64: 311-314, 1975. The specificity of the serum gamma-glutamyl transpepidase (GGT) was evaluated by its determination in 1,040 unselected adult inpatients. GGT was elevated in 139 (13.4%) patients, but was only rarely elevated in the absence of elevation of other enzymes in the routine chemistry profile. Of the elevations, 32.4% occurred in patients with primary hepatobiliary disease. An elevated serum GGT is a strong indicator of hepatobiliary dysfunction. However, proper interpretation of a serum GGT elevation requires correlation with clinical data and other tests.

Alcoholism↗